Bioinformatics data analysis code accompanying: Taylor, J.D., Barrett, N., Martinez Cuesta, S. et al. Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes. Commun Biol 7, 1179 (2024). https://doi.org/10.1038/s42003-024-06803-4
Software requirements:
- R 3.6.0 with libraries:
- devtools 2.3.2
- tidyverse 1.3.0
- yaml 2.2.1
- data.table 1.13.2
- limma 3.42.2
- ggplot2 3.3.2
- ggrepel 0.9.1
- VennDiagram 1.6.20
- (data preparation prior to differential expression analysis was performed using an in-house code)
To reproduce the data analyses, figures and tables in the paper, install the software requirements and run code.md