diff --git a/src/visiomode/config.py b/src/visiomode/config.py
index ea38b97a..18670f0d 100644
--- a/src/visiomode/config.py
+++ b/src/visiomode/config.py
@@ -5,12 +5,14 @@
 #  Copyright (c) 2024 Olivier Delree <odelree@ed.ac.uk>
 #  Distributed under the terms of the MIT Licence.
 
-import os
-import shutil
 import json
 import logging
+import os
+import shutil
 import typing
 
+import serial.tools.list_ports as ports
+
 logging.basicConfig(level=logging.INFO)
 
 DEFAULT_CONFIG = {
@@ -25,6 +27,12 @@
     "height": 800,
     "fullscreen": False,
     "devices": "devices",
+    "input_device_address": (
+        ports.comports()[1] if len(ports.comports()) > 1 else "/dev/ttyS0"
+    ),
+    "reward_device_address": (
+        ports.comports()[0] if len(ports.comports()) else "/dev/ttyS0"
+    ),
     "config_path": ".visiomode.json",
 }
 
@@ -46,6 +54,8 @@ class Config:
         height: Screen height.
         fullscreen: Fullscreen mode flag.
         devices: Path to devices directory.
+        input_device_address: Path to the input device address.
+        reward_device_address: Path to the device address.
         config_path: Path to the config.
     """
 
@@ -60,6 +70,8 @@ class Config:
     height: int
     fullscreen: bool
     devices: str
+    input_device_address: str
+    reward_device_address: str
     config_path: str
 
     _instance = None
diff --git a/src/visiomode/core.py b/src/visiomode/core.py
index f5a607c4..15397345 100644
--- a/src/visiomode/core.py
+++ b/src/visiomode/core.py
@@ -184,6 +184,17 @@ def request_listener(self):
                 logging.error("Invalid request - {}".format(request))
                 continue
             if request["type"] == "start":
+                # Update config
+                conf.Config().input_device_address = (
+                    request["data"].get("response_address")
+                    or conf.Config().input_device_address
+                )
+                conf.Config().reward_device_address = (
+                    request["data"].get("reward_address")
+                    or conf.Config().reward_device_address
+                )
+                conf.Config().save()
+
                 task = tasks.get_task(request["data"].pop("task"))
                 self.session = models.Session(
                     animal_id=request["data"].pop("animal_id"),
diff --git a/src/visiomode/devices/__init__.py b/src/visiomode/devices/__init__.py
index 6621062e..ff4d325b 100644
--- a/src/visiomode/devices/__init__.py
+++ b/src/visiomode/devices/__init__.py
@@ -2,6 +2,7 @@
 
 #  This file is part of visiomode.
 #  Copyright (c) 2020 Constantinos Eleftheriou <Constantinos.Eleftheriou@ed.ac.uk>
+#  Copyright (c) 2024 Olivier Delree <odelree@ed.ac.uk>
 #  Distributed under the terms of the MIT Licence.
 import os
 import queue
@@ -12,9 +13,20 @@
 import visiomode.plugins as plugins
 
 
-def get_available_devices():
-    """Return list of all serial devices connected to the machine."""
-    return [dev.device for dev in ports.comports()]
+def get_available_devices() -> list[str]:
+    """
+    Return list of all serial devices connected to the machine, with ones defined in the
+    config prepended.
+    """
+    # Get an ordered set of keys so that options presented to the user are more
+    # pleasingly organised.
+    return list(
+        dict.fromkeys(
+            [conf.Config().reward_device_address]
+            + [conf.Config().input_device_address]
+            + [dev.device for dev in ports.comports()]
+        ).keys()
+    )
 
 
 def get_input_device(profile_id, address=None):
diff --git a/src/visiomode/webpanel/templates/tasks/task.html b/src/visiomode/webpanel/templates/tasks/task.html
index b307cf74..47b9a039 100644
--- a/src/visiomode/webpanel/templates/tasks/task.html
+++ b/src/visiomode/webpanel/templates/tasks/task.html
@@ -11,7 +11,7 @@
         <label id="response_address_label" for="response_address">Input Device Address</label>
         <select id="response_address" class="custom-select form-control mb-3">
             {% for address in serial_devices %}
-                <option value="{{ address }}">{{ address }}</option>
+                <option value="{{ address }}" {% if loop.index == 2 %} selected {% endif %}>{{ address }}</option>
             {% endfor %}
         </select>
     </div>