local interaction improvement

[elenapapaleo]

we now annotate as uncertain cases where the mutation site is with SASA > 20% because we do not know if they can potentially interact with a interface or interactor for which we have no structural coverage. This might still retain some partially buried sites where another protein cannot get in (an example N363 in POLE). Thus an idea for improvement of this annotation is to modify the decision tree so that we include the data from fpocket and both SASA > 20% and belonging to a pocket should be criteria satisfied to go in the uncertain class, the other could be reverted to neutral as the cases of buried residues.