diff --git a/M/MIOpen/MIOpen@5.2.3/build_tarballs.jl b/M/MIOpen/MIOpen@5.2.3/build_tarballs.jl
new file mode 100644
index 00000000000..c5e6f6e2b98
--- /dev/null
+++ b/M/MIOpen/MIOpen@5.2.3/build_tarballs.jl
@@ -0,0 +1,8 @@
+using Pkg
+using BinaryBuilder
+
+include("../common.jl")
+
+build_tarballs(
+    ARGS, configure_build(v"5.2.3")...;
+    preferred_gcc_version=v"7", preferred_llvm_version=v"9")
diff --git a/M/MIOpen/MIOpen@5.2.3/bundled/patches/boost-fix.patch b/M/MIOpen/MIOpen@5.2.3/bundled/patches/boost-fix.patch
new file mode 100644
index 00000000000..2ae1f8adff0
--- /dev/null
+++ b/M/MIOpen/MIOpen@5.2.3/bundled/patches/boost-fix.patch
@@ -0,0 +1,18 @@
+diff --git a/include/miopen/config.h.in b/include/miopen/config.h.in
+index 1849b4344..d0c6f2a9b 100644
+--- a/include/miopen/config.h.in
++++ b/include/miopen/config.h.in
+@@ -117,4 +117,13 @@
+     ((HIP_PACKAGE_VERSION_MAJOR * 1000ULL + HIP_PACKAGE_VERSION_MINOR) * 1000000 + \
+      HIP_PACKAGE_VERSION_PATCH)
+ 
++/// WORKAROUND_BOOST_ISSUE_392
++/// Workaround for https://github.com/boostorg/config/issues/392#issuecomment-1109889533
++/// See also https://github.com/ROCmSoftwarePlatform/MIOpen/pull/1490#issuecomment-1109928102,
++/// https://github.com/ROCmSoftwarePlatform/MIOpen/pull/1543
++/// TODO: Remove the W/A as soon we switch to the properly fixed boost.
++#if MIOPEN_BACKEND_HIP
++#include <hip/hip_version.h>
++#endif
++
+ #endif
diff --git a/M/MIOpen/common.jl b/M/MIOpen/common.jl
new file mode 100644
index 00000000000..cc8e9a1bd76
--- /dev/null
+++ b/M/MIOpen/common.jl
@@ -0,0 +1,75 @@
+const NAME = "MIOpen"
+
+const ROCM_GIT = "https://github.com/ROCmSoftwarePlatform/MIOpen/"
+const GIT_TAGS = Dict(
+    v"5.2.3" => "28747847446955b3bab24f7fc65c1a6b863a12f12ad3a35e0312072482d38122",
+)
+
+const ROCM_PLATFORMS = [
+    Platform("x86_64", "linux"; libc="glibc", cxxstring_abi="cxx11"),
+    # TODO add, when rocBLAS 5.2.3+ is built for musl
+    # Platform("x86_64", "linux"; libc="musl", cxxstring_abi="cxx11"),
+]
+const PRODUCTS = [
+    LibraryProduct(["libMIOpen"], :libMIOpen, ["lib"]),
+    FileProduct("include/half.hpp", :libhalf),
+]
+
+function configure_build(version)
+    buildscript = raw"""
+    mv ${WORKSPACE}/srcdir/half/include/half.hpp ${prefix}/include
+    export HALF_INCLUDE_DIR=${prefix}/include
+
+    mv ${WORKSPACE}/srcdir/rocm-clang* ${prefix}/llvm/bin
+
+    cd ${WORKSPACE}/srcdir/MIOpen*/
+    atomic_patch -p1 ${WORKSPACE}/srcdir/patches/boost-fix.patch
+    mkdir build
+
+    export AMDGPU_TARGETS="gfx900;gfx906;gfx90a;gfx1010;gfx1012;gfx1030"
+    export ROCM_PATH=${prefix}
+
+    export HIP_PATH=${prefix}/hip
+    export HIP_PLATFORM=amd
+    export HIP_RUNTIME=rocclr
+    export HIP_COMPILER=clang
+
+    CXXFLAGS="${CXXFLAGS} -I${prefix}/include/rocblas" \
+    cmake -S . -B build \
+        -DCMAKE_CXX_COMPILER=${prefix}/llvm/bin/rocm-clang++ \
+        -DCMAKE_INSTALL_PREFIX=${prefix} \
+        -DCMAKE_PREFIX_PATH=${prefix} \
+        -DCMAKE_BUILD_TYPE=Release \
+        -DROCM_PATH=${ROCM_PATH} \
+        -DAMDGPU_TARGETS=${AMDGPU_TARGETS} \
+        -DBoost_USE_STATIC_LIBS=OFF \
+        -DMIOPEN_BACKEND=HIP \
+        -DMIOPEN_USE_MLIR=OFF \
+        -DHALF_INCLUDE_DIR=${HALF_INCLUDE_DIR}
+
+    make -j${nproc} -C build install
+
+    install_license ${WORKSPACE}/srcdir/MIOpen*/LICENSE.txt
+    """
+
+    sources = [
+        ArchiveSource(
+            ROCM_GIT * "archive/rocm-$(version).tar.gz", GIT_TAGS[version]),
+        ArchiveSource(
+            "https://downloads.sourceforge.net/project/half/half/2.1.0/half-2.1.0.zip",
+            "ad1788afe0300fa2b02b0d1df128d857f021f92ccf7c8bddd07812685fa07a25";
+            unpack_target="half"),
+        DirectorySource("./bundled"),
+        DirectorySource("../scripts"),
+    ]
+    dependencies = [
+        BuildDependency(PackageSpec(; name="ROCmLLVM_jll", version)),
+        BuildDependency(PackageSpec(; name="rocm_cmake_jll", version)),
+        Dependency("HIP_jll"; compat=string(version)),
+        Dependency("rocBLAS_jll"; compat=string(version)),
+        Dependency("Zlib_jll"),
+        Dependency("SQLite_jll"),
+        Dependency("boost_jll"; compat="1.79.0"),
+    ]
+    NAME, version, sources, buildscript, ROCM_PLATFORMS, PRODUCTS, dependencies
+end
diff --git a/M/MIOpen/scripts/rocm-clang++ b/M/MIOpen/scripts/rocm-clang++
new file mode 100755
index 00000000000..65d550f845d
--- /dev/null
+++ b/M/MIOpen/scripts/rocm-clang++
@@ -0,0 +1,40 @@
+#!/bin/bash
+
+ARGS=( "$@" )
+PRE_FLAGS=()
+POST_FLAGS=()
+
+PRE_FLAGS+=( -target ${target} )
+PRE_FLAGS+=( --sysroot=/opt/${target}/${target}/sys-root )
+PRE_FLAGS+=( --gcc-toolchain=/opt/${target} )
+
+if [[ " ${ARGS[@]} " != *' -x assembler '* ]]; then
+    PRE_FLAGS+=( -march=x86-64 )
+    PRE_FLAGS+=( -mtune=generic )
+fi
+
+COMPILE_BASE_DIR=/opt/${target}/${target}
+COMPILE_CPP_DIR=${COMPILE_BASE_DIR}/include/c++/*
+
+if [[ " ${ARGS[@]} " != *' -c '* ]] && [[ " ${ARGS[@]} " != *' -E '* ]] && [[ " ${ARGS[@]} " != *' -M '* ]] && [[ " ${ARGS[@]} " != *' -fsyntax-only '* ]]; then
+    POST_FLAGS+=( -rtlib=libgcc )
+    POST_FLAGS+=( -stdlib=libstdc++ )
+    POST_FLAGS+=( -fuse-ld=lld )
+fi
+
+COMPILE_BASE_DIR=/opt/${target}/${target}
+LINK_GCC_DIR=/opt/${target}/lib/gcc/${target}/*
+# Need `-isystem` to be in post flags, for `#include_next` to work.
+POST_FLAGS+=(-isystem ${COMPILE_CPP_DIR} -isystem ${COMPILE_CPP_DIR}/${target})
+POST_FLAGS+=(-B ${LINK_GCC_DIR} -L ${LINK_GCC_DIR} -L ${COMPILE_BASE_DIR}/lib64)
+
+if [[ " ${ARGS[@]} " == *"-march="* ]]; then
+    echo "BinaryBuilder: Cannot force an architecture via -march" >&2
+    exit 1
+fi
+
+if [ ${USE_CCACHE} == "true" ]; then
+    CCACHE="ccache"
+fi
+
+${CCACHE} ${prefix}/llvm/bin/clang++ "${PRE_FLAGS[@]}" "${ARGS[@]}" "${POST_FLAGS[@]}"