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Desirable Compounds Not Yet Synthesised

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MFernflower edited this page Oct 16, 2018 · 29 revisions

Links needed in this section to failed attempts,or suggestions that are promising, along with their rationale. As of Feb 2018, the following constitute the DCNYS's.

Additionally a small library of compounds was proposed by Mandrake (Anthony) in 2017 based on the idea of mimicking ATP - compounds in green boxes should have somewhat decent cellular permeability:

Background

OSM Series 3

Aims and Current Interest in Series 3

Sources of Data

Mechanism of Action, Activity and Toxicity

Mechanism of Action

Synthetic Chemistry

Synthesis of the Original Hit

Desirable Compounds Not Yet Synthesised

Structure-Activity Relationships

The Data on the Original Hit

All Analogs Evaluated to Date

Compounds Synthesised But Not Evaluated

The Surrounding Chemical Space

Misc

Funding for this Series

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