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Desirable Compounds Not Yet Synthesised

MFernflower edited this page Jan 16, 2019 · 29 revisions

Furanyl analogue:

SMILES: NC1=C2C(C=C(C3=CC=CC(S(=O)(N)=O)=C3)O2)=NC=N1 InChI=1S/C12H10N4O3S/c13-12-11-9(15-6-16-12)5-10(19-11)7-2-1-3-8(4-7)20(14,17)18/h1-6H,(H2,13,15,16)(H2,14,17,18)

Laboratory efforts are currently going towards producing the furanyl analogue of OSM-S-106 (image above) - Early discussion of synthetic chemistry, up-to-date Google Doc describing detailed synthetic progress.

Other possible molecules of interest:

The below set of compounds were proposed by Mfernflower based on the similarity of the S3 hit to the natural product ca(r)boxamycin: