diff --git a/src/client/features/search/pathway-results-view.js b/src/client/features/search/pathway-results-view.js
index a35d65a68..84670c88a 100644
--- a/src/client/features/search/pathway-results-view.js
+++ b/src/client/features/search/pathway-results-view.js
@@ -3,6 +3,7 @@ const h = require('react-hyperscript');
 const Link = require('react-router-dom').Link;
 const queryString = require('query-string');
 const _ = require('lodash');
+const classNames = require('classnames');
 
 const { ErrorMessage } = require('../../common/components/error-message');
 
@@ -19,21 +20,43 @@ class PathwayResultsView extends React.Component {
       return null;
     }
 
-    const searchList = pathwayResults.map(result => {
+    const searchList = pathwayResults.map( ( result, index ) => {
       let dsInfo = _.get( result, 'sourceInfo', '' );
       let iconUrl = dsInfo.iconUrl || '';
       let name = dsInfo.name || '';
-
-      return h('div.search-item', [
-        h('div.search-item-icon',[
-          h('img', {src: iconUrl})
+      const pathwayTitle = result.name;      
+      const topHit = index === 0;
+      const hasPreview = result.previewUrl;
+      const showPreview = topHit && hasPreview;
+    
+      let item;
+      const itemLink = children => h(Link, { className: 'plain-link', to: { pathname: '/pathways', search: queryString.stringify({ uri: result.uri }) }, target: '_blank' }, children || 'N/A');
+      const itemPreview = h('img.search-item-preview', {src: result.previewUrl});
+      const itemInfo = title => h('div.search-item-info', [
+        h('div.search-item-icon', [ 
+          h('img', {src: iconUrl}) 
         ]),
         h('div.search-item-content', [
-          h(Link, { className: 'plain-link', to: { pathname: '/pathways', search: queryString.stringify({ uri: result.uri }) }, target: '_blank' }, [result.name || 'N/A']),
+          title,         
           h('p.search-item-content-datasource', ` ${name}`),
           h('p.search-item-content-participants', `${result.numParticipants} Participants`)
         ])
       ]);
+      
+      if( showPreview ){ 
+        // Wrap the entire item in a link 
+        item = itemLink([
+          itemInfo( pathwayTitle ), 
+          itemPreview
+        ]);
+      } else {
+        // Associate the link with the content
+        item = itemInfo( itemLink( pathwayTitle ) );
+      } 
+      
+      return h('div.search-item', {
+        className: classNames({ 'preview': showPreview })
+      }, item );
     });
 
     const searchResultFilter = h('div.search-filters', [
diff --git a/src/scripts/cli.js b/src/scripts/cli.js
index 62a214f20..950f4a486 100644
--- a/src/scripts/cli.js
+++ b/src/scripts/cli.js
@@ -9,6 +9,7 @@ const fsPromises = require('fs').promises;
 const readline = require( 'readline' );
 const retry = require( 'async-retry' );
 
+const { uri2filename } = require( '../util/uri.js' );
 const logger = require( '../server/logger.js' );
 const {
   DOWNLOADS_FOLDER_NAME,
@@ -169,9 +170,6 @@ const parsePCGmtLine = line => {
   return { uri, meta, genes };
 };
 
-// Create file safe names from a uri
-const uri2filename = s => s.replace(/[^a-z0-9]/gi, '_').toLowerCase();
-
 async function getStore( ) {
   const store = {
     async save( item ){
diff --git a/src/server/external-services/pathway-commons.js b/src/server/external-services/pathway-commons.js
index 129451ac5..13ad190de 100644
--- a/src/server/external-services/pathway-commons.js
+++ b/src/server/external-services/pathway-commons.js
@@ -1,3 +1,5 @@
+const fs = require('fs');
+const path = require('path');
 const qs = require('query-string');
 const url = require('url');
 const QuickLRU = require('quick-lru');
@@ -8,6 +10,7 @@ const { cachePromise } = require('../cache');
 const { fetch } = require('../../util');
 const logger = require('../logger');
 const config = require('../../config');
+const { uri2filename } = require('../../util/uri.js');
 
 const xrefCache = new QuickLRU({ maxSize: config.PC_CACHE_MAX_SIZE });
 const queryCache = new QuickLRU({ maxSize: config.PC_CACHE_MAX_SIZE });
@@ -105,7 +108,21 @@ const addSourceInfo = async function( searchHit, dataSources ) {
   return searchHit;
 };
 
+// Fill in preview URL
+const addPreviewUrl = function( searchHit ) {
+  const { uri } = searchHit;
+  const fname = uri2filename( uri );
+  const fpath = path.resolve( config.SBGN_IMG_PATH, `${fname}.png` );
+  const hasImage = fs.existsSync( fpath );
+  if ( hasImage ){
+    const previewUrl = fpath.split( path.sep ).slice(-3).join(path.sep);
+    searchHit.previewUrl = previewUrl;
+  }
+  return searchHit;
+};
+
 const augmentSearchHits = async function( searchHits ) {
+  if( searchHits.length ) addPreviewUrl( searchHits[0] );
   const dataSources = await getDataSourcesMap();
   return Promise.all( searchHits.map( searchHit => addSourceInfo( searchHit, dataSources ) ) );
 };
diff --git a/src/styles/features/search.css b/src/styles/features/search.css
index c1d2a56dd..6db7ef31a 100644
--- a/src/styles/features/search.css
+++ b/src/styles/features/search.css
@@ -201,10 +201,18 @@
 }
 
 .search-item {
+  padding: 1em 0;
+}
+
+.search-item.preview {
+  /* background-color: var(--cloud); */
+  border: 1px solid var(--cloud-darker);
+}
+
+.search-item-info {
   display: flex;
   vertical-align: middle;
   align-items: center;
-  padding: 1em 0;
 }
 
 .search-item-icon {
@@ -238,6 +246,13 @@
   font-size: 0.66em;
 }
 
+.search-item-preview {
+  display: block;
+  margin-left: auto;
+  margin-right: auto;
+  width: 70%;
+}
+
 .loader {
   color: var(--accent-1-colour);
 }
diff --git a/src/util/uri.js b/src/util/uri.js
new file mode 100644
index 000000000..2373f1b7e
--- /dev/null
+++ b/src/util/uri.js
@@ -0,0 +1,6 @@
+// Create file safe names from a uri
+const uri2filename = s => s.replace(/[^a-z0-9]/gi, '_').toLowerCase();
+
+module.exports = {
+  uri2filename
+};
\ No newline at end of file