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Specific use case for masspy? (From James) #79

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z-haiman opened this issue Nov 6, 2018 · 0 comments
Open

Specific use case for masspy? (From James) #79

z-haiman opened this issue Nov 6, 2018 · 0 comments

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@z-haiman
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z-haiman commented Nov 6, 2018

Specific use-case of masspy, might consider making a built-in function:

Has a GEM for organism, as well as a kinetic model of a subsystem of the larger GEM.
Integrate the two of them by using the CBM to set vmax in the ODE kinetics with a pseudo rate constant that ensures the steady-state is reached in agreement with experimental data (used to parameterize GEM).

Consider having some functions built in to set a vmax of a kinetic reaction based on the steady-state FBA solution from the same model.

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