diff --git a/.changes/next-release/bugfix-s3-09efbe2a.json b/.changes/next-release/bugfix-s3-09efbe2a.json
new file mode 100644
index 0000000000..7b770c0738
--- /dev/null
+++ b/.changes/next-release/bugfix-s3-09efbe2a.json
@@ -0,0 +1,5 @@
+{
+  "type": "bugfix",
+  "category": "s3",
+  "description": "update s3 status 200 error classification"
+}
\ No newline at end of file
diff --git a/lib/services/s3.js b/lib/services/s3.js
index 0d0b11bbdc..3773481474 100644
--- a/lib/services/s3.js
+++ b/lib/services/s3.js
@@ -531,17 +531,21 @@ AWS.util.update(AWS.S3.prototype, {
    * @api private
    */
   extractErrorFrom200Response: function extractErrorFrom200Response(resp) {
-    if (!operationsWith200StatusCodeError[resp.request.operation]) return;
+    var service = this.service ? this.service : this;
+    if (!service.is200Error(resp) && !operationsWith200StatusCodeError[resp.request.operation]) {
+      return;
+    }
     var httpResponse = resp.httpResponse;
-    if (httpResponse.body && httpResponse.body.toString().match('<Error>')) {
+    var bodyString = httpResponse.body && httpResponse.body.toString() || '';
+    if (bodyString && bodyString.indexOf('</Error>') === bodyString.length - 8) {
       // Response body with '<Error>...</Error>' indicates an exception.
       // Get S3 client object. In ManagedUpload, this.service refers to
       // S3 client object.
       resp.data = null;
-      var service = this.service ? this.service : this;
       service.extractError(resp);
+      resp.error.is200Error = true;
       throw resp.error;
-    } else if (!httpResponse.body || !httpResponse.body.toString().match(/<[\w_]/)) {
+    } else if (!httpResponse.body || !bodyString.match(/<[\w_]/)) {
       // When body is empty or incomplete, S3 might stop the request on detecting client
       // side aborting the request.
       resp.data = null;
@@ -552,13 +556,54 @@ AWS.util.update(AWS.S3.prototype, {
     }
   },
 
+  /**
+   * @api private
+   * @param resp - to evaluate.
+   * @return true if the response has status code 200 but is an error.
+   */
+  is200Error: function is200Error(resp) {
+    var code = resp && resp.httpResponse && resp.httpResponse.statusCode;
+    if (code !== 200) {
+      return false;
+    }
+    try {
+      var req = resp.request;
+      var outputMembers = req.service.api.operations[req.operation].output.members;
+      var keys = Object.keys(outputMembers);
+      for (var i = 0; i < keys.length; ++i) {
+        var member = outputMembers[keys[i]];
+        if (member.type === 'binary' && member.isStreaming) {
+          return false;
+        }
+      }
+
+      var body = resp.httpResponse.body;
+      if (body && body.byteLength !== undefined) {
+        if (body.byteLength < 15 || body.byteLength > 3000) {
+          // body is too short or long to be an error message.
+          return false;
+        }
+      }
+      if (!body) {
+        return false;
+      }
+      var bodyString = body.toString();
+      if (bodyString.indexOf('</Error>') === bodyString.length - 8) {
+        return true;
+      }
+    } catch (e) {
+      return false;
+    }
+    return false;
+  },
+
   /**
    * @return [Boolean] whether the error can be retried
    * @api private
    */
   retryableError: function retryableError(error, request) {
-    if (operationsWith200StatusCodeError[request.operation] &&
-        error.statusCode === 200) {
+    if (error.is200Error ||
+       (operationsWith200StatusCodeError[request.operation] && error.statusCode === 200)) {
       return true;
     } else if (request._requestRegionForBucket &&
         request.service.bucketRegionCache[request._requestRegionForBucket]) {
diff --git a/scripts/region-checker/allowlist.js b/scripts/region-checker/allowlist.js
index b7d173bfb5..4b61e6a79d 100644
--- a/scripts/region-checker/allowlist.js
+++ b/scripts/region-checker/allowlist.js
@@ -44,13 +44,13 @@ var allowlist = {
         263,
         276,
         282,
-        642,
-        644,
-        763,
-        774,
-        775,
-        776,
-        781
+        687,
+        689,
+        808,
+        819,
+        820,
+        821,
+        826
     ],
     '/token/sso_token_provider.js': [
         60