Draft network file: Ectodata/ectocyc.sbml Seeds file: Ectodata/seeds.sbml Targets file: Ectodata/targets.sbml
51 unproducible targets ARACHIDIC_ACID ARACHIDONIC_ACID ARG ASN CIT CPD__45__13814 CPD__45__14292 CPD__45__7836 CPD__45__8117 CPD__45__8119 CPD__45__8120 CPD__45__8121 CPD__45__9245 CPD__45__9247 CYS DOCOSANOATE D__45__ALANINE GLC GLN GLT GLUTATHIONE GLY GLYCERATE GLYCEROL GLYCOLLATE HIS HOMO__45__SER ILE LEU LINOLEIC_ACID LINOLENIC_ACID LYS L__45__ALPHA__45__ALANINE L__45__ASPARTATE L__45__ORNITHINE MANNITOL MET OLEATE__45__CPD PALMITATE PHE PRO SER STEARIC_ACID SUC THR THREO__45__DS__45__ISO__45__CITRATE TRP TYR VAL _4__45__AMINO__45__BUTYRATE _5Z8Z11Z14Z17Z__45__EICOSAPENTAENOATE
Repair db file: Ectodata/metacyc_16-5.sbml
4 unreconstructable targets CPD__45__13814 CPD__45__14292 CPD__45__8119 DOCOSANOATE
47 reconstructable targets ARACHIDIC_ACID ARACHIDONIC_ACID ARG ASN CIT CPD__45__7836 CPD__45__8117 CPD__45__8120 CPD__45__8121 CPD__45__9245 CPD__45__9247 CYS D__45__ALANINE GLC GLN GLT GLUTATHIONE GLY GLYCERATE GLYCEROL GLYCOLLATE HIS HOMO__45__SER ILE LEU LINOLEIC_ACID LINOLENIC_ACID LYS L__45__ALPHA__45__ALANINE L__45__ASPARTATE L__45__ORNITHINE MANNITOL MET OLEATE__45__CPD PALMITATE PHE PRO SER STEARIC_ACID SUC THR THREO__45__DS__45__ISO__45__CITRATE TRP TYR VAL _4__45__AMINO__45__BUTYRATE _5Z8Z11Z14Z17Z__45__EICOSAPENTAENOATE
3 essential reactions for target ARACHIDIC_ACID RXN__45__9520 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
11 essential reactions for target ARACHIDONIC_ACID RXN__45__12777 RXN__45__12968 RXN__45__12969 RXN__45__12971 RXN__45__13435 RXN__45__8346 RXN__45__9520 RXN__45__9655 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target ARG
0 essential reactions for target ASN
0 essential reactions for target CIT
6 essential reactions for target CPD__45__7836 RXN__45__10727 RXN__45__9520 RXN__45__9533 RXN__45__9537 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
5 essential reactions for target CPD__45__8117 RXN__45__9520 RXN__45__9655 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _4__46__2__46__1__46__59__45__RXN
10 essential reactions for target CPD__45__8120 RXN__45__12777 RXN__45__12968 RXN__45__12969 RXN__45__12971 RXN__45__13435 RXN__45__9520 RXN__45__9655 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target CPD__45__8121
4 essential reactions for target CPD__45__9245 RXN__45__9520 RXN__45__9550 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
6 essential reactions for target CPD__45__9247 RXN__45__9520 RXN__45__9555 RXN__45__9557 RXN__45__9558 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target CYS
0 essential reactions for target D__45__ALANINE
0 essential reactions for target GLC
0 essential reactions for target GLN
0 essential reactions for target GLT
0 essential reactions for target GLUTATHIONE
0 essential reactions for target GLY
0 essential reactions for target GLYCERATE
0 essential reactions for target GLYCEROL
0 essential reactions for target GLYCOLLATE
2 essential reactions for target HIS HISTCYCLOHYD__45__RXN HISTIDPHOS__45__RXN
0 essential reactions for target HOMO__45__SER
0 essential reactions for target ILE
0 essential reactions for target LEU
5 essential reactions for target LINOLEIC_ACID RXN__45__9520 RXN__45__9655 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target LINOLENIC_ACID
0 essential reactions for target LYS
0 essential reactions for target L__45__ALPHA__45__ALANINE
0 essential reactions for target L__45__ASPARTATE
0 essential reactions for target L__45__ORNITHINE
0 essential reactions for target MANNITOL
0 essential reactions for target MET
5 essential reactions for target OLEATE__45__CPD RXN__45__9520 RXN__45__9655 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _4__46__2__46__1__46__59__45__RXN
4 essential reactions for target PALMITATE RXN__45__9520 RXN__45__9549 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target PHE
0 essential reactions for target PRO
0 essential reactions for target SER
3 essential reactions for target STEARIC_ACID RXN__45__9520 RXN__45__9655 _4__46__2__46__1__46__59__45__RXN
0 essential reactions for target SUC
0 essential reactions for target THR
0 essential reactions for target THREO__45__DS__45__ISO__45__CITRATE
0 essential reactions for target TRP
0 essential reactions for target TYR
0 essential reactions for target VAL
0 essential reactions for target _4__45__AMINO__45__BUTYRATE
0 essential reactions for target _5Z8Z11Z14Z17Z__45__EICOSAPENTAENOATE
Overall 21 essential reactions found RXN__45__12968 HISTCYCLOHYD__45__RXN _1__46__14__46__19__46__2__45__RXN RXN__45__9655 RXN__45__9533 _4__46__2__46__1__46__59__45__RXN RXN__45__13435 RXN__45__12969 RXN__45__9555 HISTIDPHOS__45__RXN RXN__45__8346 RXN__45__12777 RXN__45__10727 RXN__45__9550 RXN__45__9558 _3__46__1__46__2__46__14__45__RXN RXN__45__9520 RXN__45__9549 RXN__45__9557 RXN__45__12971 RXN__45__9537
One minimal completion of size 48 FATTY__45__ACYL__45__COA__45__SYNTHASE__45__RXN FORMYLMETHIONINE__45__DEFORMYLASE__45__RXN GDPMANMANHYDRO__45__RXN GLUC1PURIDYLTRANS__45__RXN GLUTDECARBOX__45__RXN HISTCYCLOHYD__45__RXN HISTIDPHOS__45__RXN MALONYL__45__ACPDECARBOX__45__RXN PHOSPHOGLYCERATE__45__PHOSPHATASE__45__RXN PREPHENATEDEHYDROG__45__RXN RIB5PISOM__45__RXN RXN__45__10663 RXN__45__10727 RXN__45__12487 RXN__45__12766 RXN__45__12777 RXN__45__12793 RXN__45__12794 RXN__45__12968 RXN__45__12969 RXN__45__12971 RXN__45__13242 RXN__45__13261 RXN__45__13431 RXN__45__13435 RXN__45__7968 RXN__45__8346 RXN__45__9520 RXN__45__9533 RXN__45__9537 RXN__45__9548 RXN__45__9549 RXN__45__9550 RXN__45__9555 RXN__45__9557 RXN__45__9558 RXN__45__9634 RXN__45__9655 RXN__45__9673 _1__46__14__46__19__46__2__45__RXN _1__46__1__46__3__46__40__45__RXN _3__46__1__46__2__46__14__45__RXN _3__46__4__46__13__46__17__45__RXN _3__46__4__46__14__46__1__45__RXN _3__46__4__46__19__46__7__45__RXN _4__46__2__46__1__46__58__45__RXN _4__46__2__46__1__46__59__45__RXN _4__46__2__46__1__46__61__45__RXN
Intersection of cardinality minimal completions FORMYLMETHIONINE__45__DEFORMYLASE__45__RXN GLUTDECARBOX__45__RXN HISTCYCLOHYD__45__RXN HISTIDPHOS__45__RXN RIB5PISOM__45__RXN RXN__45__10727 RXN__45__12766 RXN__45__12777 RXN__45__12968 RXN__45__12969 RXN__45__12971 RXN__45__13242 RXN__45__13261 RXN__45__13435 RXN__45__8346 RXN__45__9520 RXN__45__9533 RXN__45__9537 RXN__45__9548 RXN__45__9549 RXN__45__9550 RXN__45__9555 RXN__45__9557 RXN__45__9558 RXN__45__9634 RXN__45__9655 RXN__45__9673 _1__46__14__46__19__46__2__45__RXN _3__46__1__46__2__46__14__45__RXN _3__46__4__46__14__46__1__45__RXN _3__46__4__46__19__46__7__45__RXN _4__46__2__46__1__46__58__45__RXN _4__46__2__46__1__46__59__45__RXN _4__46__2__46__1__46__61__45__RXN
Union of cardinality minimal completions ACP__45__S__45__ACETYLTRANSFER__45__RXN CYCLOHEXADIENYL__45__DEHYDROGENASE__45__RXN FATTY__45__ACID__45__SYNTHASE__45__RXN FATTY__45__ACYL__45__COA__45__SYNTHASE__45__RXN FORMYLMETHIONINE__45__DEFORMYLASE__45__RXN GDPMANMANHYDRO__45__RXN GLUC1PADENYLTRANS__45__RXN GLUC1PURIDYLTRANS__45__RXN GLUCISOM__45__RXN GLUCOKIN__45__RXN GLUCOSE__45__1__45__PHOSPHATE__45__PHOSPHODISMUTASE__45__RXN GLUCOSE__45__6__45__PHOSPHATASE__45__RXN GLUTDECARBOX__45__RXN HISTCYCLOHYD__45__RXN HISTIDPHOS__45__RXN MALONYL__45__ACPDECARBOX__45__RXN MANNITOL__45__1__45__PHOSPHATASE__45__RXN MANNITOL__45__2__45__DEHYDROGENASE__45__NADP__43____45__RXN MANNITOL__45__2__45__DEHYDROGENASE__45__RXN MANNOSE__45__6__45__PHOSPHATE__45__6__45__REDUCTASE__45__RXN MANNPDEHYDROG__45__RXN PHOSPHOGLYCERATE__45__PHOSPHATASE__45__RXN PREPHENATEDEHYDROG__45__RXN PREPHENATE__45__ASP__45__TRANSAMINE__45__RXN PREPHENATE__45__DEHYDROGENASE__45__NADP__43____45__RXN PREPHENATE__45__TRANSAMINE__45__RXN RIB5PISOM__45__RXN RXN__45__10663 RXN__45__10727 RXN__45__10770 RXN__45__11508 RXN__45__12361 RXN__45__12486 RXN__45__12487 RXN__45__12755 RXN__45__12766 RXN__45__12777 RXN__45__12793 RXN__45__12794 RXN__45__12968 RXN__45__12969 RXN__45__12971 RXN__45__13242 RXN__45__13261 RXN__45__13431 RXN__45__13435 RXN__45__5682 RXN__45__7968 RXN__45__8346 RXN__45__8347 RXN__45__8349 RXN__45__8350 RXN__45__8389 RXN__45__9520 RXN__45__9533 RXN__45__9537 RXN__45__9548 RXN__45__9549 RXN__45__9550 RXN__45__9555 RXN__45__9557 RXN__45__9558 RXN__45__9634 RXN__45__9655 RXN__45__9673 SHIKIMATE__45__5__45__DEHYDROGENASE__45__RXN SUGAR__45__TERMINAL__45__PHOSPHATASE__45__RXN TYRAMINOTRANS__45__RXN TYROSINE__45__AMINOTRANSFERASE__45__RXN _1__46__14__46__19__46__2__45__RXN _1__46__1__46__1__46__255__45__RXN _1__46__1__46__3__46__40__45__RXN _2__46__3__46__1__46__180__45__RXN _2__46__4__46__1__46__216__45__RXN _2__46__7__46__1__46__142__45__RXN _2__46__7__46__7__46__34__45__RXN _3__45__PHOSPHOGLYCERATE__45__PHOSPHATASE__45__RXN _3__46__1__46__2__46__14__45__RXN _3__46__4__46__13__46__17__45__RXN _3__46__4__46__13__46__19__45__RXN _3__46__4__46__13__46__4__45__RXN _3__46__4__46__13__46__5__45__RXN _3__46__4__46__14__46__1__45__RXN _3__46__4__46__19__46__7__45__RXN _4__46__2__46__1__46__58__45__RXN _4__46__2__46__1__46__59__45__RXN _4__46__2__46__1__46__61__45__RXN