Unable to add custom modification

[cctsou]

Hi,

I would like to add TMTpro 16-plex and a custom modification. I was able to add them as user-modifications and save them into user modifications.txt file. But I did not find a way to add the user modifications into the default modification list, how do I do that? version (DeNovoGUI 1.16.8)

Thank you very much!!

[hbarsnes]

The user-defined modifications will always be separate from the default modifications. But why do you need the TMTpro 16-plex modification to be included in the list of default modifications? You should be able to select modifications from both lists (as the two are simply merged) when running a de novo search? However, your custom modifications will not (yet) be included in the "Most Used Modifications" list, so be sure to change the option to "All Modifications" when selecting the modifications in the De Novo Settings dialog.