Enhanced filtering for false positives

v1.0.3

Smaller change in alignment processing

v1.0.2: Bug Fix in Tree/merging

New features:

1. Automatic distance computation
2. STD computations and filtering of breakpoints to detect artifacts
3. Detection of small translocated elements
4. New SV type
5. Enhanced small indel calling

Bug Fixes:

1. Merging of SVs within the tree

v1.0.1

Reduce false calls over using nanopore reads.
Changes in the VCF file to support IGV display for translocations.

Sniffles v1.0.0

Major release 1.0.0:

• Faster reconstruction and scanning of alignment
• Improved handling of smaller SVs
• Genotyping (alpha version)
• Read phasing (alpha version)

Pre Publication release of Sniffles

The current version was benchmarked over several simulated and real data sets. However, I have not finished my work on sniffles yet. Any suggestions/reports are more then welcome.

Sniffles further lack a realignment step that will be incorporated within 1-2 months.
Thank you
Fritz