diff --git a/cmake/python.cmake b/cmake/python.cmake
index fb3d7d9f7b5..e7e2851ac55 100644
--- a/cmake/python.cmake
+++ b/cmake/python.cmake
@@ -31,7 +31,7 @@ if(${SWIG_VERSION} VERSION_GREATER_EQUAL 4)
   list(APPEND CMAKE_SWIG_FLAGS "-doxygen")
 endif()
 
-if(UNIX AND NOT APPLE)
+if(UNIX AND NOT APPLE AND NOT (CMAKE_SYSTEM_NAME STREQUAL "OpenBSD"))
   if (CMAKE_SIZEOF_VOID_P EQUAL 8)
     list(APPEND CMAKE_SWIG_FLAGS "-DSWIGWORDSIZE64")
   else()