diff --git a/setup.py b/setup.py
index 1de20941..255d9fa5 100644
--- a/setup.py
+++ b/setup.py
@@ -42,7 +42,7 @@
     long_description=README,
     platforms="Posix; MacOS X",
     include_package_data=True,
-    install_requires=("protobuf >= 3.19.0, <5.0.0dev",),
+    install_requires=("protobuf >= 3.19.0, <6.0.0dev",),
     extras_require={
         "testing": [
             "google-api-core >= 1.31.5",