This repository contains raw data that was used in the research paper:
Yongli Shan, John H. Abel, Yan Li, Mariko Izumo, Kimberly H. Cox, Byeongha Jeong, Seung-Hee Yoo, David P. Olson, Francis J. Doyle III, Joseph S. Takahashi. (2020) Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony. Neuron.
Includes five folders for the five genotypes analyzed in the article: VIP-Cre, VIP-Bmal1-/-, AVP-Cre, AVP-Bmal1-/- and VIP/AVP-Bmal1-/-. And every subfolder contains imaging results of each SCN imaging experiment.
Each dataset includes 14 files of three types:
| File Name suffix | Raw Data |
|---|---|
_signal.csv |
Bioluminescence signals of single cells |
_XY.csv |
X,Y locations of single cells |
_polygon.csv |
Contours of an SCN slice, left and right lobe |
Data analysis tools and code are available through another repository:
Code for per2py data analysis https://github.com/johnabel/per2py
Includes four folders for the four categories of genotypes analyzed in the article: VIP-Bmal1-/-, AVP-Bmal1-/-, VIP/AVP-Bmal1-/- and control.
Behaviroal records were acquired with Clocklab and analyzed with Clocklab Analysis: https://www.actimetrics.com/products/clocklab/