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<!DOCTYPE html>
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<head>
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<title>Kircher Lab</title>
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<div class="wrapper"><a class="site-title" rel="author" href="/">Computational Genome Biology & Regulatory Genomics</a>
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<h1 class="post-title">Welcome to Kircher Lab!</h1>
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<img src="assets/images/group2024.jpg" style="max-width:100%;" alt="Group picture" />
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<h4 class="post-title">UzL/UKSH Regulatory Genomics at the Baltic coast and BIH Computational Genome Biology in the heart of Berlin</h4>
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<p>
The Kircher Lab studies genetic variant effects throughout the genome and across variant classes.
We are developing computational methods to predict the deleteriousness of genetic variants, study the effects of non-coding
sequence alterations (e.g. using massively parallel reporter assays and functional read outs) and analyze
cell-type contributions of cell-free DNA. We can be found at two locations. We are part of the Institute for Human Genetics
of the University of Lübeck (UzL) and the University Medical Center Schleswig Holstein (UKSH), where we are
<a href="contact.html">located</a> in the BMF building on the Campus Lübeck. We are also part of the
<a href="https://www.bihealth.org">Berlin Institute of Health (BIH)</a>, the translational research institute of
<a href="https://www.charite.de/en">Charité - Universitätsmedizin Berlin</a>, where we are
<a href="contact.html">located</a> at the Charité Campus Mitte.
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If you want to learn more about our work, check our <a href="research.html">research</a> or some of our recent <a href="publications.html">publications</a>.
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<p>You are excited about our research topics and want to join the lab? <a href="contact.html">Please reach out.</a></p>
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