diff --git a/server/database.js b/server/database.js
index 3b7646de8c..44005d6e9e 100644
--- a/server/database.js
+++ b/server/database.js
@@ -184,10 +184,18 @@ class Database {
 
     /**
      * @typedef {string|undefined} envString
-     * @param {{type: "sqlite"} | {type:envString, hostname:envString, port:envString, database:envString, username:envString, password:envString}} dbConfig the database configuration that should be written
+     * @param {{type: "sqlite"} | {type:envString, hostname:envString, port:envString, database:envString, username:envString, password:envString, caFilePath:envString}} dbConfig the database configuration that should be written
      * @returns {void}
      */
     static writeDBConfig(dbConfig) {
+        // Move CA file to the data directory
+        if (dbConfig.caFilePath) {
+            const dataCaFilePath = path.join(Database.dataDir, "mariadb-ca.pem");
+            fs.renameSync(dbConfig.caFilePath, dataCaFilePath);
+            dbConfig.caFilePath = dataCaFilePath;
+            dbConfig.ssl = undefined;
+            dbConfig.caFile = undefined;
+        }
         fs.writeFileSync(path.join(Database.dataDir, "db-config.json"), JSON.stringify(dbConfig, null, 4));
     }
 
@@ -259,11 +267,22 @@ class Database {
                 throw Error("Invalid database name. A database name can only consist of letters, numbers and underscores");
             }
 
+            let sslConfig = null;
+            let serverCa = undefined;
+            if (dbConfig.caFilePath) {
+                serverCa = [ fs.readFileSync(dbConfig.caFilePath, "utf8") ];
+                sslConfig = {
+                    rejectUnauthorized: true,
+                    ca: serverCa
+                };
+            }
+
             const connection = await mysql.createConnection({
                 host: dbConfig.hostname,
                 port: dbConfig.port,
                 user: dbConfig.username,
                 password: dbConfig.password,
+                ssl: sslConfig
             });
 
             await connection.execute("CREATE DATABASE IF NOT EXISTS " + dbConfig.dbName + " CHARACTER SET utf8mb4");
@@ -277,7 +296,9 @@ class Database {
                     user: dbConfig.username,
                     password: dbConfig.password,
                     database: dbConfig.dbName,
+                    ssl: sslConfig,
                     timezone: "Z",
+                    //ssl: sslConfig,
                     typeCast: function (field, next) {
                         if (field.type === "DATETIME") {
                             // Do not perform timezone conversion
diff --git a/server/setup-database.js b/server/setup-database.js
index 483f2c9a49..ddf664a19f 100644
--- a/server/setup-database.js
+++ b/server/setup-database.js
@@ -77,6 +77,7 @@ class SetupDatabase {
             dbConfig.dbName = process.env.UPTIME_KUMA_DB_NAME;
             dbConfig.username = process.env.UPTIME_KUMA_DB_USERNAME;
             dbConfig.password = process.env.UPTIME_KUMA_DB_PASSWORD;
+            dbConfig.caFilePath = process.env.UPTIME_KUMA_DB_CA_CERT;
             Database.writeDBConfig(dbConfig);
         }
 
@@ -206,13 +207,43 @@ class SetupDatabase {
                         return;
                     }
 
+                    // Prevent someone from injecting a CA file path not generated by the code below
+                    if (dbConfig.caFilePath) {
+                        dbConfig.caFilePath = undefined;
+                    }
+
+                    if (dbConfig.caFile) {
+                        const base64Data = dbConfig.caFile.replace(/^data:application\/octet-stream;base64,/, "");
+                        const binaryData = Buffer.from(base64Data, "base64").toString("binary");
+                        const tempCaDirectory = fs.mkdtempSync("kuma-ca-");
+                        dbConfig.caFilePath = path.join(tempCaDirectory, "ca.pem");
+                        try {
+                            fs.writeFileSync(dbConfig.caFilePath, binaryData, "binary");
+                        } catch (err) {
+
+                            response.status(400).json("Cannot write CA file: " + err.message);
+                            this.runningSetup = false;
+                            return;
+                        }
+                        dbConfig.ssl = {
+                            rejectUnauthorized: true,
+                            ca: [ fs.readFileSync(dbConfig.caFilePath) ]
+                        };
+                    }
+
                     // Test connection
                     try {
+                        let sslConfig = null;
+                        if (dbConfig.ssl) {
+                            sslConfig = dbConfig.ssl;
+                        }
+
                         const connection = await mysql.createConnection({
                             host: dbConfig.hostname,
                             port: dbConfig.port,
                             user: dbConfig.username,
                             password: dbConfig.password,
+                            ssl: sslConfig
                         });
                         await connection.execute("SELECT 1");
                         connection.end();
diff --git a/src/lang/en.json b/src/lang/en.json
index e215f1031f..1c92ebbb7d 100644
--- a/src/lang/en.json
+++ b/src/lang/en.json
@@ -4,6 +4,7 @@
     "setupDatabaseEmbeddedMariaDB": "You don't need to set anything. This docker image has embedded and configured MariaDB for you automatically. Uptime Kuma will connect to this database via unix socket.",
     "setupDatabaseMariaDB": "Connect to an external MariaDB database. You need to set the database connection information.",
     "setupDatabaseSQLite": "A simple database file, recommended for small-scale deployments. Prior to v2.0.0, Uptime Kuma used SQLite as the default database.",
+    "configureMariaCaFile": "You will sometimes need to provide a CA certificate to connect to database with 'require-secure-transport' on. Such as when using Azure MySql flexible servers. You can upload the CA file that will be used to enable a secure connection.",
     "settingUpDatabaseMSG": "Setting up the database. It may take a while, please be patient.",
     "dbName": "Database Name",
     "Settings": "Settings",
diff --git a/src/pages/SetupDatabase.vue b/src/pages/SetupDatabase.vue
index 81738a98b5..c4906d6411 100644
--- a/src/pages/SetupDatabase.vue
+++ b/src/pages/SetupDatabase.vue
@@ -90,8 +90,12 @@
                         <input id="floatingInput" v-model="dbConfig.dbName" type="text" class="form-control" required>
                         <label for="floatingInput">{{ $t("dbName") }}</label>
                     </div>
-                </template>
 
+                    <div class="mb2 mt-3 short">
+                        <p class="mb-2">{{ $t("configureMariaCaFile") }}</p>
+                        <input id="ca-input" type="file" accept="application/x-pem-file, .pem" class="form-control" @change="onCaFileChange">
+                    </div>
+                </template>
                 <button class="btn btn-primary mt-4 short" type="submit" :disabled="disabledButton">
                     {{ $t("Next") }}
                 </button>
@@ -117,6 +121,7 @@ export default {
                 username: "",
                 password: "",
                 dbName: "kuma",
+                caFile: ""
             },
             info: {
                 needSetup: false,
@@ -178,6 +183,15 @@ export default {
             }
         },
 
+        onCaFileChange(e) {
+            const fileReader = new FileReader();
+            fileReader.onload = () => {
+                this.dbConfig.caFile = fileReader.result;
+                console.log(this.dbConfig.caFile);
+            };
+            fileReader.readAsDataURL(e.target.files[0]);
+        },
+
         test() {
             this.$root.toastError("not implemented");
         }
@@ -186,6 +200,22 @@ export default {
 </script>
 
 <style lang="scss" scoped>
+@import "../assets/vars.scss";
+
+.dark {
+    #ca-input {
+        &::file-selector-button {
+            color: $primary;
+            background-color: $dark-bg;
+        }
+
+        &:hover:not(:disabled):not([readonly])::file-selector-button {
+            color: $dark-font-color2;
+            background-color: $primary;
+        }
+    }
+}
+
 .form-container {
     display: flex;
     align-items: center;