diff --git a/src/ontology/mp-edit.owl b/src/ontology/mp-edit.owl
index cd8da168..277aec95 100644
--- a/src/ontology/mp-edit.owl
+++ b/src/ontology/mp-edit.owl
@@ -11847,6 +11847,16 @@ Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014533>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014534>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014535>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014536>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014537>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014538>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014539>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014540>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014541>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014542>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014543>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014544>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014545>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014546>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020000>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020002>))
@@ -16559,6 +16569,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0000194> "increased circulating calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0000194> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000178>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0000194> <http://purl.obolibrary.org/obo/MP_0001562>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0000194> <http://purl.obolibrary.org/obo/MP_0014537>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0000195> (decreased circulating calcium level)
 
@@ -16577,6 +16588,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0000195> "decreased circulating calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0000195> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000178>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0000195> <http://purl.obolibrary.org/obo/MP_0001562>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0000195> <http://purl.obolibrary.org/obo/MP_0014538>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0000198> (decreased circulating phosphate level)
 
@@ -16594,6 +16606,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0000198> "decreased circulating phosphate level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0000198> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_26020> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/mpath#part_of> <http://purl.obolibrary.org/obo/UBERON_0000178>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0000198> <http://purl.obolibrary.org/obo/MP_0001565>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0000198> <http://purl.obolibrary.org/obo/MP_0014546>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0000199> (abnormal circulating serum albumin level)
 
@@ -29393,6 +29406,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#inSubset> <htt
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0001566> "increased circulating phosphate level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0001566> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_26020> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000178>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0001566> <http://purl.obolibrary.org/obo/MP_0001565>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0001566> <http://purl.obolibrary.org/obo/MP_0014545>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0001569> (abnormal circulating bilirubin level)
 
@@ -42950,6 +42964,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0002986> "decreased urine calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0002986> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001088>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0002986> <http://purl.obolibrary.org/obo/MP_0002985>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0002986> <http://purl.obolibrary.org/obo/MP_0014538>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0002987> (abnormal urine osmolality)
 
@@ -43716,6 +43731,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0003066> "increased liver copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0003066> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002107>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0003066> <http://purl.obolibrary.org/obo/MP_0003065>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0003066> <http://purl.obolibrary.org/obo/MP_0014539>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0003067> (decreased liver copper level)
 
@@ -43728,6 +43744,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0003067> "decreased liver copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0003067> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002107>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0003067> <http://purl.obolibrary.org/obo/MP_0003065>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0003067> <http://purl.obolibrary.org/obo/MP_0014540>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0003068> (enlarged kidney)
 
@@ -62287,6 +62304,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0004866> "increased platelet calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0004866> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/CL_0000233>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0004866> <http://purl.obolibrary.org/obo/MP_0004865>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0004866> <http://purl.obolibrary.org/obo/MP_0014537>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0004867> (decreased platelet calcium level)
 
@@ -62297,6 +62315,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0004867> "decreased platelet calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0004867> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/CL_0000233>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0004867> <http://purl.obolibrary.org/obo/MP_0004865>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0004867> <http://purl.obolibrary.org/obo/MP_0014538>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0004868> (increased endometrial carcinoma incidence)
 
@@ -68351,6 +68370,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0005441> "increased urine calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0005441> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001088>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0005441> <http://purl.obolibrary.org/obo/MP_0002985>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0005441> <http://purl.obolibrary.org/obo/MP_0014537>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0005442> (obsolete abnormal pyramidal neuron morphology)
 
@@ -70492,7 +70512,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0005638> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0005638> "MP:0005638")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0005638> "hemochromatosis")
-SubClassOf(<http://purl.obolibrary.org/obo/MP_0005638> <http://purl.obolibrary.org/obo/MP_0001770>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0005638> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0005639> (hemosiderosis)
 
@@ -70501,7 +70521,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0005639> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0005639> "MP:0005639")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0005639> "hemosiderosis")
-SubClassOf(<http://purl.obolibrary.org/obo/MP_0005639> <http://purl.obolibrary.org/obo/MP_0001770>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0005639> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0005640> (abnormal mean corpuscular hemoglobin concentration)
 
@@ -84871,6 +84891,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0008743> "decreased liver iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0008743> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002107>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0008743> <http://purl.obolibrary.org/obo/MP_0008738>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0008743> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0008744> (abnormal B cell anergy)
 
@@ -85602,6 +85623,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0008808> "decreased spleen iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0008808> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002106>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0008808> <http://purl.obolibrary.org/obo/MP_0008739>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0008808> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0008809> (increased spleen iron level)
 
@@ -85615,6 +85637,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0008809> "increased spleen iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0008809> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002106>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0008809> <http://purl.obolibrary.org/obo/MP_0008739>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0008809> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0008810> (increased circulating iron level)
 
@@ -102743,6 +102766,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010243> "increased kidney copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010243> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002113>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010243> <http://purl.obolibrary.org/obo/MP_0010242>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010243> <http://purl.obolibrary.org/obo/MP_0014539>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010244> (decreased kidney copper level)
 
@@ -102758,6 +102782,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010244> "decreased kidney copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010244> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002113>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010244> <http://purl.obolibrary.org/obo/MP_0010242>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010244> <http://purl.obolibrary.org/obo/MP_0014540>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010245> (abnormal spleen perifollicular zone morphology)
 
@@ -102794,6 +102819,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010247> "increased intestine copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010247> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000160>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010247> <http://purl.obolibrary.org/obo/MP_0010246>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010247> <http://purl.obolibrary.org/obo/MP_0014539>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010248> (decreased intestine copper level)
 
@@ -102807,6 +102833,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010248> "decreased intestine copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000160>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010248> <http://purl.obolibrary.org/obo/MP_0010246>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010248> <http://purl.obolibrary.org/obo/MP_0014540>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010249> (lactation failure)
 
@@ -104591,6 +104618,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010375> "increased kidney iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010375> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002113>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010375> <http://purl.obolibrary.org/obo/MP_0008742>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010375> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010376> (decreased kidney iron level)
 
@@ -104606,6 +104634,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010376> "decreased kidney iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010376> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0002113>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010376> <http://purl.obolibrary.org/obo/MP_0008742>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010376> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010377> (abnormal gut flora balance)
 
@@ -116692,6 +116721,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0011214> "increased brain copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0011214> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000955>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0011214> <http://purl.obolibrary.org/obo/MP_0011213>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0011214> <http://purl.obolibrary.org/obo/MP_0014539>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0011215> (decreased brain copper level)
 
@@ -116705,6 +116735,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0011215> "decreased brain copper level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0011215> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_28694> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000955>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0011215> <http://purl.obolibrary.org/obo/MP_0011213>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0011215> <http://purl.obolibrary.org/obo/MP_0014540>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0011216> (abnormal brainstem copper level)
 
@@ -142395,6 +142426,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0013302> "increased pancreas iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0013302> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001264>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0013302> <http://purl.obolibrary.org/obo/MP_0013301>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0013302> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0013303> (decreased pancreas iron level)
 
@@ -142406,6 +142438,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0013303> "decreased pancreas iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0013303> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0001264>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0013303> <http://purl.obolibrary.org/obo/MP_0013301>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0013303> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0013304> (osteophytes)
 
@@ -154691,6 +154724,122 @@ AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014536> "decr
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014536> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_46662>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0014536> <http://purl.obolibrary.org/obo/MP_0000192>)
 
+# Class: <http://purl.obolibrary.org/obo/MP_0014537> (increased calcium level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0003-4606-0597>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014537> "increase in the concentration of calcium in the body or bodily fluids")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014537> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014537> "2024-08-08T18:54:05Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014537> "elevated calcium level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014537> "MP:0014537")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014537> "increased calcium level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014537> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_22984>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014537> <http://purl.obolibrary.org/obo/MP_0014535>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014537> <http://purl.obolibrary.org/obo/MP_0020879>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014538> (decreased calcium level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0003-4606-0597>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014538> "reduction in the concentration of calcium in the body or bodily fluids")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014538> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014538> "2024-08-08T18:54:18Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014538> "reduced calcium level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014538> "MP:0014538")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014538> "decreased calcium level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014538> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_22984>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014538> <http://purl.obolibrary.org/obo/MP_0014536>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014538> <http://purl.obolibrary.org/obo/MP_0020879>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014539> (increased copper level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "CHEBI:28694") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014539> "increase in the concentration in the body of the metallic element atom that has formula Cu, and normally occurs as a cofactor for a number of proteins including amine oxidases and chaperone proteins")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014539> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014539> "2024-08-08T19:02:07Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014539> "elevated copper level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014539> "MP:0014539")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014539> "increased copper level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014539> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28694>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014539> <http://purl.obolibrary.org/obo/MP_0003952>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014540> (decreased copper level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "CHEBI:28694") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014540> "reduction in the concentration in the body of the metallic element atom that has formula Cu, and normally occurs as a cofactor for a number of proteins including amine oxidases and chaperone proteins")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014540> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014540> "2024-08-08T19:02:20Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014540> "reduced copper level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014540> "MP:0014540")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014540> "decreased copper level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014540> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28694>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014540> <http://purl.obolibrary.org/obo/MP_0003952>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014541> (increased iron level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0-683-40008-8") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014541> "increase in the concentrations of the metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins and is an essential component of enzymes such as catalase, peroxidase, and various cytochromes")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014541> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014541> "2024-08-08T19:22:13Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014541> "elevated iron level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014541> "MP:0014541")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014541> "increased iron level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014541> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18248>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014541> <http://purl.obolibrary.org/obo/MP_0001770>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014541> <http://purl.obolibrary.org/obo/MP_0014535>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014542> (decreased iron level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "ISBN:0-683-40008-8") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014542> "reduction in the concentrations of the metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins and is an essential component of enzymes such as catalase, peroxidase, and various cytochromes")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014542> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014542> "2024-08-08T19:22:28Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014542> "reduced iron level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014542> "MP:0014542")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014542> "decreased iron level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014542> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18248>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014542> <http://purl.obolibrary.org/obo/MP_0001770>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014542> <http://purl.obolibrary.org/obo/MP_0014536>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014543> (increased manganese level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "CHEBI:25154") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014543> "increase in the concentration of manganese in the body")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014543> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014543> "2024-08-08T19:35:55Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014543> "elevated manganese level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014543> "MP:0014543")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014543> "increased manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014543> <http://purl.obolibrary.org/obo/MP_0014535>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014543> <http://purl.obolibrary.org/obo/MP_0030593>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014544> (decreased manganese level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "CHEBI:25154") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014544> "reduction in the concentration of manganese in the body")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014544> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014544> "2024-08-08T19:36:08Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014544> "reduced manganese level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014544> "MP:0014544")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014544> "decreased manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014544> <http://purl.obolibrary.org/obo/MP_0014536>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014544> <http://purl.obolibrary.org/obo/MP_0030593>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014545> (increased phosphate level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0003-4606-0597>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014545> "increase in the concentration of phosphate (salt or ester of phosphoric acid) in the body")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014545> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014545> "2024-08-08T19:45:01Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014545> "elevated phosphate level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014545> "MP:0014545")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014545> "increased phosphate level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014545> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26020>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014545> <http://purl.obolibrary.org/obo/MP_0014535>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014545> <http://purl.obolibrary.org/obo/MP_0020885>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014546> (decreased phosphate level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0003-4606-0597>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014546> "reduction in the concentration of phosphate (salt or ester of phosphoric acid) in the body")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014546> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014546> "2024-08-08T19:45:17Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014546> "reduced phosphate level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014546> "MP:0014546")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014546> "decreased phosphate level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014546> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26020>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014546> <http://purl.obolibrary.org/obo/MP_0014536>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014546> <http://purl.obolibrary.org/obo/MP_0020885>)
+
 # Class: <http://purl.obolibrary.org/obo/MP_0020000> (abnormal response to antigen)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0001-5208-3432>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0020000> "anomaly in the immune response after exposure to an antigen")
@@ -158935,6 +159084,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020365> "increased brain iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020365> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000955>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020365> <http://purl.obolibrary.org/obo/MP_0008811>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020365> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020366> (decreased brain iron level)
 
@@ -158945,6 +159095,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020366> "decreased brain iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020366> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000955>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020366> <http://purl.obolibrary.org/obo/MP_0008811>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020366> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020367> (increased heart iron level)
 
@@ -158957,6 +159108,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020367> "increased heart iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020367> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000948>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020367> <http://purl.obolibrary.org/obo/MP_0008741>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020367> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020368> (decreased heart iron level)
 
@@ -158969,6 +159121,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020368> "decreased heart iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020368> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000948>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020368> <http://purl.obolibrary.org/obo/MP_0008741>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020368> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020369> (increased intestinal iron level)
 
@@ -158979,6 +159132,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020369> "increased intestinal iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020369> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000160>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020369> <http://purl.obolibrary.org/obo/MP_0008740>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020369> <http://purl.obolibrary.org/obo/MP_0014541>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020370> (abnormal glymphatic system morphology)
 
@@ -159110,6 +159264,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020385> "decreased intestinal iron level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020385> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_18248> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://purl.obolibrary.org/obo/UBERON_0000160>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020385> <http://purl.obolibrary.org/obo/MP_0008740>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020385> <http://purl.obolibrary.org/obo/MP_0014542>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020386> (adipose tissue inflammation)
 
@@ -167346,6 +167501,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0021126> "MP:0021126")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0021126> "increased phosphocholine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0021126> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18132>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0021126> <http://purl.obolibrary.org/obo/MP_0014545>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0021126> <http://purl.obolibrary.org/obo/MP_0021125>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0021127> (decreased phosphocholine level)
@@ -167357,6 +167513,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0021127> "MP:0021127")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0021127> "decreased phosphocholine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0021127> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18132>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0021127> <http://purl.obolibrary.org/obo/MP_0014546>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0021127> <http://purl.obolibrary.org/obo/MP_0021125>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0021128> (increased choline level)
@@ -167508,6 +167665,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0021140> "MP:0021140")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0021140> "increased cardiac muscle calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0021140> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/mpath#part_of> <http://purl.obolibrary.org/obo/UBERON_0001133>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0021140> <http://purl.obolibrary.org/obo/MP_0014537>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0021140> <http://purl.obolibrary.org/obo/MP_0021139>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0021141> (decreased cardiac muscle calcium level)
@@ -167526,6 +167684,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0021141> "MP:0021141")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0021141> "decreased cardiac muscle calcium level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0021141> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/CHEBI_22984> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/mpath#part_of> <http://purl.obolibrary.org/obo/UBERON_0001133>))) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0021141> <http://purl.obolibrary.org/obo/MP_0014538>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0021141> <http://purl.obolibrary.org/obo/MP_0021139>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0021142> (abnormal brain N-acetyl-L-aspartic acid level)
@@ -176615,6 +176774,7 @@ AnnotationAssertion(<http://purl.org/dc/elements/1.1/date> <http://purl.obolibra
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030595> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030595> "MP:0030595")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030595> "increased brain manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030595> <http://purl.obolibrary.org/obo/MP_0014543>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030595> <http://purl.obolibrary.org/obo/MP_0030594>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030596> (decreased brain manganese level)
@@ -176626,6 +176786,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030596> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030596> "MP:0030596")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030596> "decreased brain manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030596> <http://purl.obolibrary.org/obo/MP_0014544>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030596> <http://purl.obolibrary.org/obo/MP_0030594>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030597> (abnormal liver manganese level)
@@ -176651,6 +176812,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030598> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030598> "MP:0030598")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030598> "increased liver manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030598> <http://purl.obolibrary.org/obo/MP_0014543>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030598> <http://purl.obolibrary.org/obo/MP_0030597>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030599> (decreased liver manganese level)
@@ -176666,6 +176828,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030599> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030599> "MP:0030599")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030599> "decreased liver manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030599> <http://purl.obolibrary.org/obo/MP_0014544>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030599> <http://purl.obolibrary.org/obo/MP_0030597>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030600> (abnormal circulating manganese level)
@@ -176687,6 +176850,7 @@ AnnotationAssertion(<http://purl.org/dc/elements/1.1/date> <http://purl.obolibra
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030601> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030601> "MP:0030601")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030601> "increased circulating manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030601> <http://purl.obolibrary.org/obo/MP_0014543>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030601> <http://purl.obolibrary.org/obo/MP_0030600>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030602> (decreased circulating manganese level)
@@ -176698,6 +176862,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030602> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030602> "MP:0030602")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030602> "decreased circulating manganese level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030602> <http://purl.obolibrary.org/obo/MP_0014544>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030602> <http://purl.obolibrary.org/obo/MP_0030600>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030603> (increased sperm number)