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DESCRIPTION
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DESCRIPTION
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Package: hipathia
Title: HiPathia: High-throughput Pathway Analysis
Version: 2.13.1
Authors@R: c(person("Marta R.", "Hidalgo", email = "[email protected]", role = c("aut", "cre")),
person("José", "Carbonell-Caballero", role = c("ctb")),
person("Francisco", "Salavert", role = c("ctb")),
person("Alicia", "Amadoz", role = c("ctb")),
person("Çankut", "Cubuk", role = c("ctb")),
person("Joaquin", "Dopazo", role = c("ctb")))
Description: Hipathia is a method for the computation of signal transduction along
signaling pathways from transcriptomic data. The method is based on an
iterative algorithm which
is able to compute the signal intensity passing through the nodes of a
network by taking into account the level of expression of each gene and
the intensity of the signal arriving to it. It also provides a new approach
to functional analysis allowing to compute the signal arriving to the
functions annotated to each pathway.
Depends: R (>= 3.6), igraph (>= 1.0.1), AnnotationHub(>= 2.6.5), MultiAssayExperiment(>= 1.4.9), SummarizedExperiment(>= 1.8.1)
License: GPL-2
Encoding: UTF-8
LazyData: true
Imports:
coin, stats, limma, grDevices, utils, graphics, preprocessCore, servr, DelayedArray, matrixStats, methods, S4Vectors
RoxygenNote: 7.0.0
Suggests: BiocStyle, knitr, rmarkdown, testthat
VignetteBuilder: knitr
biocViews: Pathways, GraphAndNetwork, GeneExpression, GeneSignaling, GO