diff --git a/NAMESPACE b/NAMESPACE index 1a33c88..bdb1e37 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -3,15 +3,29 @@ export("name<-") export(AbsoluteAbundanceData) export(AbundanceData) +export(Anopheles_albimanus) export(BONUS) export(Bangladesh) export(Collection) export(Collections) +export(DailyBaby) export(DiabImmune) +export(ECAM) +export(EcoCF) export(FARMM) +export(GEMS1) +export(HMP_V1V3) +export(HMP_V3V5) export(HMP_WGS) +export(Leishmaniasis) +export(MALED_2yr) +export(MALED_diarrhea) +export(MORDOR) +export(Malaysia_helminth) export(MbioDataset) export(NICU_NEC) +export(PIH_Uganda) +export(PretermInfantResistome1) export(SampleMetadata) export(getAbundances) export(getCollection) diff --git a/R/data.R b/R/data.R index 09915ad..87d3404 100644 --- a/R/data.R +++ b/R/data.R @@ -170,4 +170,365 @@ #' @source #' @name NICU_NEC #' @export -"NICU_NEC" \ No newline at end of file +"NICU_NEC" + +#' GEMS1 Case Control +#' +#' The Global Enteric Multicenter Study (GEMS) investigated the cause, incidence and impact of +#' moderate to severe diarrheal (MSD) disease in children. 514 MSD cases and 493 endemic controls from Bangladesh, +#' The Gambia, Kenya and Mali were included. 1007 stool samples; V1-V2 region of 16S rRNA gene. +#' Prospective, age-stratified, matched case-control design. Additional clinical and epidemiologic +#' data for the same participants is available at ClinEpiDB.org. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `GEMS1` +#' A MbioDataset object with 12 metadata variables, 1015 16S stool samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name GEMS1 +#' @export +"GEMS1" + +#' DailyBaby +#' +#' Near daily fecal specimens collected from term infants during the first year of life. +#' 12 healthy term infants born in Oslo, Norway. +#' 2684 stool samples total, with an average of 224 samples (range 116–267) per infant. +#' Prospective cohort design. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `DailyBaby` +#' A MbioDataset object with 17 metadata variables, 2684 16S stool samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name DailyBaby +#' @export +"DailyBaby" + +#' Anopheles albimanus +#' +#' This study assessed the impact of pyrethroid exposure on the internal and cuticle microbiome of Anopheles albimanusi. +#' 125 samples, each pool of 3 mosquitos. V3-V4 region of 16S rRNA gene. +#' Adult and larval Anopheles albimanus collected in and around Las Cruces, Guatemala. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `Anopheles_albimanus` +#' A MbioDataset object with 12 metadata variables, 125 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name Anopheles_albimanus +#' @export +"Anopheles_albimanus" + +#' ECAM +#' +#' The Early Childhood Antibiotics and the Microbiome (ECAM) study set out to identify the impact of antibiotics, +#' delivery mode and diet on the infant gut Microbiome. Prospective cohort design in healthy humans from USA. +#' 43 infants sampled during the first two years of life. 1216 samples of various types; V4 region of 16S rRNA gene. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `ECAM` +#' A MbioDataset object with 27 metadata variables, 1216 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name ECAM +#' @export +"ECAM" + +#' Eco-CF +#' +#' The Ecology of Cystic Fibrosis (Eco-CF) study profiled the microbiome in pediatric CF patients. +#' 169 pediatric cystic fibrosis patients seen over a four year period at Columbia Univeristy Medical Center in NYC, USA. +#' 844 samples, including sputum, oral swabs and bronchoalveolar lavage (BAL) fluid; V4 region of 16S rRNA gene. +#' Prospective cohort design. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `EcoCF` +#' A MbioDataset object with 77 metadata variables, 844 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name EcoCF +#' @export +"EcoCF" + +#' HMP Phase 1 (V1-V3) +#' +#' The Human Microbiome Project (HMP) profiled microbial communities across diverse habitats on the human body. +#' 242 healthly adult volunteers sampled at approximately 15 different body sites. +#' 3156 samples of various types; V1-V3 region of 16S rRNA gene. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `HMP_V1V3` +#' A MbioDataset object with 11 metadata variables, 3045 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name HMP_V1V3 +#' @export +"HMP_V1V3" + +#' HMP Phase 1 (V3-V5) +#' +#' The Human Microbiome Project (HMP) profiled microbial communities across diverse habitats on the human body. +#' 242 healthly adult volunteers sampled at approximately 15 different body sites. +#' 5826 samples of various types; V3-V5 region of 16S rRNA gene. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `HMP_V3V5` +#' A MbioDataset object with 13 metadata variables, 5462 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name HMP_V3V5 +#' @export +"HMP_V3V5" + +#' Human cutaneous leishmaniasis +#' +#' This study explored the skin microbiome during human cutaneous leishmaniasis. +#' 45 patients with cutaneous leishmaniasis. +#' 128 skin swabs collected from affected and unaffected skin; V1-V3 region of 16S rRNA gene. +#' Case-control (restrospective) design in patients seen at a field hospital +#' (Clinica em Leishmaniose Dr. Jackson Costa) in Corte de Pedra, Bahia, Brazil. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `Leishmaniasis` +#' A MbioDataset object with 16 metadata variables, 128 16S samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name Leishmaniasis +#' @export +"Leishmaniasis" + +#' MAL-ED 0-2yr +#' +#' This study set out to define the normal maturation of the gut microbiome during the first 2 years of postnatal life. +#' 50 children from four sites in the MAL-ED study: Brazil, India, Peru and South Africa. +#' 1091 stool samples; V4 region of 16S rRNA gene. +#' Prospective cohort design with monthly sampling for the first ~2 years of life. +#' Additional clinical and epidemiologic data for the same participants is available at ClinEpiDB.org. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `MALED_2yr` +#' A MbioDataset object with 16 metadata variables, 1091 16S stool samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name MALED_2yr +#' @export +"MALED_2yr" + +#' MAL-ED diarrhea +#' +#' This study set out to define the consequence of diarrhea on maturation of the gut +#' microbiome during the first 2 years of postnatal life. +#' 271 children from the Amazonian lowlands near Iquitos, Peru +#' 928 stool samples; V4 region of 16S rRNA gene. +#' Prospective cohort design with samples obtained at postnatal months 6, 12, 18, and 24 +#' Additional clinical and epidemiologic data for the same participants is available at ClinEpiDB.org. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `MALED_diarrhea` +#' A MbioDataset object with 36 metadata variables, 928 16S stool samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name MALED_diarrhea +#' @export +"MALED_diarrhea" + +#' Malaysia helminth +#' +#' The Malaysia Helminth study profiled gut metagenomes of indigenous and +#' non-indigenous individuals originating from 5 villages +#' 407 adult and pediatric participants from 5 villages +#' (Bangkong, Tanjung Sepat, Rasau, Legong, and Judah), and Kuala Lumpur +#' 650 stool samples; 'shotgun' metagenomic sequencing. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `Malaysia_helminth` +#' A MbioDataset object with 28 metadata variables, 650 shotgun stool samples. +#' It contains the following collections: \cr +#' "WGS 4th level EC metagenome abundance data" \cr +#' "WGS Metagenome enzyme pathway abundance data" \cr +#' "WGS Metagenome enzyme pathway coverage data" \cr +#' "WGS Genus" \cr +#' "WGS Species" \cr +#' "WGS Family" \cr +#' "WGS Order" \cr +#' "WGS Phylum" \cr +#' "WGS Class" \cr +#' "WGS Kingdom" \cr +#' "WGS Normalized number of taxon-specific sequence matches" \cr +#' @source +#' @name Malaysia_helminth +#' @export +"Malaysia_helminth" + +#' MORDOR phase 1 +#' +#' The Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) I +#' metagenome study evaluated the impact of mass azithromycin administration on the gut microbiome in children +#' 574 pediatric (preschool) participants from 30 Nigerien communities +#' Rectal swabs; 'shotgun' metagenomic sequencing of RNA. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `MORDOR` +#' A MbioDataset object with 10 metadata variables, 574 shotgun stool samples. +#' It contains the following collections: \cr +#' "WGS 4th level EC metagenome abundance data" \cr +#' "WGS Metagenome enzyme pathway abundance data" \cr +#' "WGS Metagenomeenzyme pathway coverage data" \cr +#' "WGS Genus" \cr +#' "WGS Species" \cr +#' "WGS Family" \cr +#' "WGS Order" \cr +#' "WGS Phylum" \cr +#' "WGS Class" \cr +#' "WGS Kingdom" \cr +#' "WGS Normalized number of taxon-specific sequence matches" \cr +#' @source +#' @name MORDOR +#' @export +"MORDOR" + +#' PIH Uganda +#' +#' This study profiled microbes present in the cerebrospinal fluid (CSF) of pediatric patients +#' with infectious and non-infectious hydrocephalus. 92 children from Uganda, including 58 with +#' postinfectious hydrocephalus (PIH) and 34 with non-postinfectious hydrocephalus (NPIH). +#' 92 cerebrospinal fluid (CSF) samples retained in this workflow; V1-V2 region of 16S rRNA gene. +#' Case-control (retrospective) design with samples collected in the first ~100 days of life. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `PIH_Uganda` +#' A MbioDataset object with 11 metadata variables, 92 CSF samples. +#' It contains the following collections: \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name PIH_Uganda +#' @export +"PIH_Uganda" + +#' Preterm Infant Resistome 1 +#' +#' The Preterm Infant Resistome I study used 16S rRNA marker gene sequencing and shotgun +#' metagenomics to profile the stool metagenome in preterm infants (born < 33 weeks gestational age) +#' stratified by antibiotic use during their hospitalization. +#' 84 preterm infant patients seen at the Washington University School of Medicine in St. Louis, MO, USA. +#' 399 stool samples; 'shotgun' metagenomic sequencing. +#' 103/399 stool samples; V4 16S rRNA gene sequencing. +#' Prospective cohort design. +#' +#' Website Release 32. (2023 May 30) +#' +#' @format ## `PretermInfantResistome1` +#' A MbioDataset object with 64 metadata variables, 399 shotgun stool samples, 103 16S stool samples. +#' It contains the following collections: \cr +#' "WGS 4th level EC metagenome abundance data" \cr +#' "WGS Metagenomeenzyme pathway abundance data" \cr +#' "WGS Metagenomeenzyme pathway coverage data" \cr +#' "WGS Genus" \cr +#' "WGS Species" \cr +#' "WGS Family" \cr +#' "WGS Order" \cr +#' "WGS Phylum" \cr +#' "WGS Class" \cr +#' "WGS Kingdom" \cr +#' "WGS Normalized number of taxon-specific sequence matches" \cr +#' "16S Order" \cr +#' "16S Genus" \cr +#' "16S Family" \cr +#' "16S Species" \cr +#' "16S Class" \cr +#' "16S Phylum" \cr +#' "16S Kingdom" \cr +#' @source +#' @name PretermInfantResistome1 +#' @export +"PretermInfantResistome1" \ No newline at end of file diff --git a/R/sysdata.rda b/R/sysdata.rda index b9807fd..0906c5e 100644 Binary files a/R/sysdata.rda and b/R/sysdata.rda differ diff --git a/man/Anopheles_albimanus.Rd b/man/Anopheles_albimanus.Rd new file mode 100644 index 0000000..12a1f68 --- /dev/null +++ b/man/Anopheles_albimanus.Rd @@ -0,0 +1,35 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{Anopheles_albimanus} +\alias{Anopheles_albimanus} +\title{Anopheles albimanus} +\format{ +\subsection{\code{Anopheles_albimanus}}{ + +A MbioDataset object with 12 metadata variables, 125 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_36cb9bab56/new/download} +} +\usage{ +Anopheles_albimanus +} +\description{ +This study assessed the impact of pyrethroid exposure on the internal and cuticle microbiome of Anopheles albimanusi. +125 samples, each pool of 3 mosquitos. V3-V4 region of 16S rRNA gene. +Adult and larval Anopheles albimanus collected in and around Las Cruces, Guatemala. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/DailyBaby.Rd b/man/DailyBaby.Rd new file mode 100644 index 0000000..4247b2a --- /dev/null +++ b/man/DailyBaby.Rd @@ -0,0 +1,36 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{DailyBaby} +\alias{DailyBaby} +\title{DailyBaby} +\format{ +\subsection{\code{DailyBaby}}{ + +A MbioDataset object with 17 metadata variables, 2684 16S stool samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_5a4f8a1791/new/download} +} +\usage{ +DailyBaby +} +\description{ +Near daily fecal specimens collected from term infants during the first year of life. +12 healthy term infants born in Oslo, Norway. +2684 stool samples total, with an average of 224 samples (range 116–267) per infant. +Prospective cohort design. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/ECAM.Rd b/man/ECAM.Rd new file mode 100644 index 0000000..62bcd9d --- /dev/null +++ b/man/ECAM.Rd @@ -0,0 +1,35 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{ECAM} +\alias{ECAM} +\title{ECAM} +\format{ +\subsection{\code{ECAM}}{ + +A MbioDataset object with 27 metadata variables, 1216 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_accd1b80f6/new/download} +} +\usage{ +ECAM +} +\description{ +The Early Childhood Antibiotics and the Microbiome (ECAM) study set out to identify the impact of antibiotics, +delivery mode and diet on the infant gut Microbiome. Prospective cohort design in healthy humans from USA. +43 infants sampled during the first two years of life. 1216 samples of various types; V4 region of 16S rRNA gene. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/EcoCF.Rd b/man/EcoCF.Rd new file mode 100644 index 0000000..5a61555 --- /dev/null +++ b/man/EcoCF.Rd @@ -0,0 +1,36 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{EcoCF} +\alias{EcoCF} +\title{Eco-CF} +\format{ +\subsection{\code{EcoCF}}{ + +A MbioDataset object with 77 metadata variables, 844 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_5a4f8a1791/new/download} +} +\usage{ +EcoCF +} +\description{ +The Ecology of Cystic Fibrosis (Eco-CF) study profiled the microbiome in pediatric CF patients. +169 pediatric cystic fibrosis patients seen over a four year period at Columbia Univeristy Medical Center in NYC, USA. +844 samples, including sputum, oral swabs and bronchoalveolar lavage (BAL) fluid; V4 region of 16S rRNA gene. +Prospective cohort design. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/GEMS1.Rd b/man/GEMS1.Rd new file mode 100644 index 0000000..55984e6 --- /dev/null +++ b/man/GEMS1.Rd @@ -0,0 +1,37 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{GEMS1} +\alias{GEMS1} +\title{GEMS1 Case Control} +\format{ +\subsection{\code{GEMS1}}{ + +A MbioDataset object with 12 metadata variables, 1015 16S stool samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_a5167b81e3/new/download} +} +\usage{ +GEMS1 +} +\description{ +The Global Enteric Multicenter Study (GEMS) investigated the cause, incidence and impact of +moderate to severe diarrheal (MSD) disease in children. 514 MSD cases and 493 endemic controls from Bangladesh, +The Gambia, Kenya and Mali were included. 1007 stool samples; V1-V2 region of 16S rRNA gene. +Prospective, age-stratified, matched case-control design. Additional clinical and epidemiologic +data for the same participants is available at ClinEpiDB.org. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/HMP_V1V3.Rd b/man/HMP_V1V3.Rd new file mode 100644 index 0000000..c347826 --- /dev/null +++ b/man/HMP_V1V3.Rd @@ -0,0 +1,35 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{HMP_V1V3} +\alias{HMP_V1V3} +\title{HMP Phase 1 (V1-V3)} +\format{ +\subsection{\code{HMP_V1V3}}{ + +A MbioDataset object with 11 metadata variables, 3045 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_570856e10e/new/download} +} +\usage{ +HMP_V1V3 +} +\description{ +The Human Microbiome Project (HMP) profiled microbial communities across diverse habitats on the human body. +242 healthly adult volunteers sampled at approximately 15 different body sites. +3156 samples of various types; V1-V3 region of 16S rRNA gene. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/HMP_V3V5.Rd b/man/HMP_V3V5.Rd new file mode 100644 index 0000000..36cce96 --- /dev/null +++ b/man/HMP_V3V5.Rd @@ -0,0 +1,35 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{HMP_V3V5} +\alias{HMP_V3V5} +\title{HMP Phase 1 (V3-V5)} +\format{ +\subsection{\code{HMP_V3V5}}{ + +A MbioDataset object with 13 metadata variables, 5462 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_ca4404e155/new/download} +} +\usage{ +HMP_V3V5 +} +\description{ +The Human Microbiome Project (HMP) profiled microbial communities across diverse habitats on the human body. +242 healthly adult volunteers sampled at approximately 15 different body sites. +5826 samples of various types; V3-V5 region of 16S rRNA gene. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/Leishmaniasis.Rd b/man/Leishmaniasis.Rd new file mode 100644 index 0000000..8f75d80 --- /dev/null +++ b/man/Leishmaniasis.Rd @@ -0,0 +1,37 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{Leishmaniasis} +\alias{Leishmaniasis} +\title{Human cutaneous leishmaniasis} +\format{ +\subsection{\code{Leishmaniasis}}{ + +A MbioDataset object with 16 metadata variables, 128 16S samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_75221fce95/new/download} +} +\usage{ +Leishmaniasis +} +\description{ +This study explored the skin microbiome during human cutaneous leishmaniasis. +45 patients with cutaneous leishmaniasis. +128 skin swabs collected from affected and unaffected skin; V1-V3 region of 16S rRNA gene. +Case-control (restrospective) design in patients seen at a field hospital +(Clinica em Leishmaniose Dr. Jackson Costa) in Corte de Pedra, Bahia, Brazil. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/MALED_2yr.Rd b/man/MALED_2yr.Rd new file mode 100644 index 0000000..8d767af --- /dev/null +++ b/man/MALED_2yr.Rd @@ -0,0 +1,37 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{MALED_2yr} +\alias{MALED_2yr} +\title{MAL-ED 0-2yr} +\format{ +\subsection{\code{MALED_2yr}}{ + +A MbioDataset object with 16 metadata variables, 1091 16S stool samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_72c94486c6/new/download} +} +\usage{ +MALED_2yr +} +\description{ +This study set out to define the normal maturation of the gut microbiome during the first 2 years of postnatal life. +50 children from four sites in the MAL-ED study: Brazil, India, Peru and South Africa. +1091 stool samples; V4 region of 16S rRNA gene. +Prospective cohort design with monthly sampling for the first ~2 years of life. +Additional clinical and epidemiologic data for the same participants is available at ClinEpiDB.org. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/MALED_diarrhea.Rd b/man/MALED_diarrhea.Rd new file mode 100644 index 0000000..6d282e4 --- /dev/null +++ b/man/MALED_diarrhea.Rd @@ -0,0 +1,38 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{MALED_diarrhea} +\alias{MALED_diarrhea} +\title{MAL-ED diarrhea} +\format{ +\subsection{\code{MALED_diarrhea}}{ + +A MbioDataset object with 36 metadata variables, 928 16S stool samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_2e56313a65/new/download} +} +\usage{ +MALED_diarrhea +} +\description{ +This study set out to define the consequence of diarrhea on maturation of the gut +microbiome during the first 2 years of postnatal life. +271 children from the Amazonian lowlands near Iquitos, Peru +928 stool samples; V4 region of 16S rRNA gene. +Prospective cohort design with samples obtained at postnatal months 6, 12, 18, and 24 +Additional clinical and epidemiologic data for the same participants is available at ClinEpiDB.org. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/MORDOR.Rd b/man/MORDOR.Rd new file mode 100644 index 0000000..2f2acb1 --- /dev/null +++ b/man/MORDOR.Rd @@ -0,0 +1,40 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{MORDOR} +\alias{MORDOR} +\title{MORDOR phase 1} +\format{ +\subsection{\code{MORDOR}}{ + +A MbioDataset object with 10 metadata variables, 574 shotgun stool samples. +It contains the following collections: \cr +"WGS 4th level EC metagenome abundance data" \cr +"WGS Metagenome enzyme pathway abundance data" \cr +"WGS Metagenomeenzyme pathway coverage data" \cr +"WGS Genus" \cr +"WGS Species" \cr +"WGS Family" \cr +"WGS Order" \cr +"WGS Phylum" \cr +"WGS Class" \cr +"WGS Kingdom" \cr +"WGS Normalized number of taxon-specific sequence matches" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_39d3629e79/new/download} +} +\usage{ +MORDOR +} +\description{ +The Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) I +metagenome study evaluated the impact of mass azithromycin administration on the gut microbiome in children +574 pediatric (preschool) participants from 30 Nigerien communities +Rectal swabs; 'shotgun' metagenomic sequencing of RNA. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/Malaysia_helminth.Rd b/man/Malaysia_helminth.Rd new file mode 100644 index 0000000..6bc6528 --- /dev/null +++ b/man/Malaysia_helminth.Rd @@ -0,0 +1,41 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{Malaysia_helminth} +\alias{Malaysia_helminth} +\title{Malaysia helminth} +\format{ +\subsection{\code{Malaysia_helminth}}{ + +A MbioDataset object with 28 metadata variables, 650 shotgun stool samples. +It contains the following collections: \cr +"WGS 4th level EC metagenome abundance data" \cr +"WGS Metagenome enzyme pathway abundance data" \cr +"WGS Metagenome enzyme pathway coverage data" \cr +"WGS Genus" \cr +"WGS Species" \cr +"WGS Family" \cr +"WGS Order" \cr +"WGS Phylum" \cr +"WGS Class" \cr +"WGS Kingdom" \cr +"WGS Normalized number of taxon-specific sequence matches" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_abcf1b1d90/new/download} +} +\usage{ +Malaysia_helminth +} +\description{ +The Malaysia Helminth study profiled gut metagenomes of indigenous and +non-indigenous individuals originating from 5 villages +407 adult and pediatric participants from 5 villages +(Bangkong, Tanjung Sepat, Rasau, Legong, and Judah), and Kuala Lumpur +650 stool samples; 'shotgun' metagenomic sequencing. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/PIH_Uganda.Rd b/man/PIH_Uganda.Rd new file mode 100644 index 0000000..39d2b56 --- /dev/null +++ b/man/PIH_Uganda.Rd @@ -0,0 +1,37 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{PIH_Uganda} +\alias{PIH_Uganda} +\title{PIH Uganda} +\format{ +\subsection{\code{PIH_Uganda}}{ + +A MbioDataset object with 11 metadata variables, 92 CSF samples. +It contains the following collections: \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_d00b1afb83/new/download} +} +\usage{ +PIH_Uganda +} +\description{ +This study profiled microbes present in the cerebrospinal fluid (CSF) of pediatric patients +with infectious and non-infectious hydrocephalus. 92 children from Uganda, including 58 with +postinfectious hydrocephalus (PIH) and 34 with non-postinfectious hydrocephalus (NPIH). +92 cerebrospinal fluid (CSF) samples retained in this workflow; V1-V2 region of 16S rRNA gene. +Case-control (retrospective) design with samples collected in the first ~100 days of life. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets} diff --git a/man/PretermInfantResistome1.Rd b/man/PretermInfantResistome1.Rd new file mode 100644 index 0000000..e4f6166 --- /dev/null +++ b/man/PretermInfantResistome1.Rd @@ -0,0 +1,50 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/data.R +\docType{data} +\name{PretermInfantResistome1} +\alias{PretermInfantResistome1} +\title{Preterm Infant Resistome 1} +\format{ +\subsection{\code{PretermInfantResistome1}}{ + +A MbioDataset object with 64 metadata variables, 399 shotgun stool samples, 103 16S stool samples. +It contains the following collections: \cr +"WGS 4th level EC metagenome abundance data" \cr +"WGS Metagenomeenzyme pathway abundance data" \cr +"WGS Metagenomeenzyme pathway coverage data" \cr +"WGS Genus" \cr +"WGS Species" \cr +"WGS Family" \cr +"WGS Order" \cr +"WGS Phylum" \cr +"WGS Class" \cr +"WGS Kingdom" \cr +"WGS Normalized number of taxon-specific sequence matches" \cr +"16S Order" \cr +"16S Genus" \cr +"16S Family" \cr +"16S Species" \cr +"16S Class" \cr +"16S Phylum" \cr +"16S Kingdom" \cr +} +} +\source{ +\url{https://microbiomedb.org/mbio/app/workspace/analyses/DS_d1b9f788dc/new/download} +} +\usage{ +PretermInfantResistome1 +} +\description{ +The Preterm Infant Resistome I study used 16S rRNA marker gene sequencing and shotgun +metagenomics to profile the stool metagenome in preterm infants (born < 33 weeks gestational age) +stratified by antibiotic use during their hospitalization. +84 preterm infant patients seen at the Washington University School of Medicine in St. Louis, MO, USA. +399 stool samples; 'shotgun' metagenomic sequencing. +103/399 stool samples; V4 16S rRNA gene sequencing. +Prospective cohort design. +} +\details{ +Website Release 32. (2023 May 30) +} +\keyword{datasets}