Channel Metadata Antibody Role Valid Value

[PozhidayevaDarya]

Information

In the submission of GeoMx Channel Metadata, the submitter reached out with a request:

Antibody Role (col G): “secondary antibody” is inaccurate: Syto13 is not an antibody at all. It is a cell-permeant dye/stain that exhibits enhanced green fluorescence when bound to nucleic acid. Not sure how to fix col G; neither option given is valid:

Possible to leave it blank (ie. make it not required)
Or better add “N/A” as an option
Out or reach I know, ideally this header would be more useful if more flexible and it was called “Molecular Probe Type” (then options could be primary antibody, secondary antibody, dye/stain..).

RRID Identifier (col J): Syto13 is not an antibody and the RRID ID doesn’t seem to include non-antibody molecular probes. ”AB _0000000” – would be fine in combination with I and K edits as noted.

Proposed change:

Add an additional valid value to the Antibody Role Attribute - "Neither - Dye/Stain"
Add "Not Applicable" as valid value to RRID Identifier Attribute

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Additional context

PR is linked here: #432

Implementation checklist

• Branch created
• HTAN.model.csv editied and pushed
• HTAN.model.jsonld validated and created by Github action
• PR opened
• PR approved
• PR merged into main
• New Component added to ncihtan/HTAN-data-curator (if required)
• DCA update requested
• DCA updated

[aclayton555]

I see this was added mid-sprint. If possible, let's try to wrap this up as part of our 24-6 sprint, which ends 2024.06.28

[PozhidayevaDarya]

@aclayton555 Thank you!