diff --git a/package-lock.json b/package-lock.json
index af148e55c7..0150abba92 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -6760,13 +6760,13 @@
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-      "resolved": "https://registry.npmjs.org/@fastify/express/-/express-3.0.0.tgz",
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+      "resolved": "https://registry.npmjs.org/@fastify/express/-/express-4.0.1.tgz",
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       "dev": true,
       "dependencies": {
-        "express": "^4.17.1",
-        "fastify-plugin": "^4.0.0"
+        "express": "^4.18.3",
+        "fastify-plugin": "^5.0.0"
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     "node_modules/@fastify/fast-json-stringify-compiler": {
@@ -18811,9 +18811,9 @@
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-      "resolved": "https://registry.npmjs.org/fastify-plugin/-/fastify-plugin-4.5.1.tgz",
-      "integrity": "sha512-stRHYGeuqpEZTL1Ef0Ovr2ltazUT9g844X5z/zEBFLG8RYlpDiOCIG+ATvYEp+/zmc7sN29mcIMp8gvYplYPIQ==",
+      "version": "5.0.1",
+      "resolved": "https://registry.npmjs.org/fastify-plugin/-/fastify-plugin-5.0.1.tgz",
+      "integrity": "sha512-HCxs+YnRaWzCl+cWRYFnHmeRFyR5GVnJTAaCJQiYzQSDwK9MgJdyAsuL3nh0EWRCYMgQ5MeziymvmAhUHYHDUQ==",
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@@ -37704,7 +37704,7 @@
         "@opentelemetry/semantic-conventions": "^1.27.0"
       },
       "devDependencies": {
-        "@fastify/express": "^3.0.0",
+        "@fastify/express": "^4.0.0",
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@@ -44603,13 +44603,13 @@
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-      "version": "3.0.0",
-      "resolved": "https://registry.npmjs.org/@fastify/express/-/express-3.0.0.tgz",
-      "integrity": "sha512-Ug6aulXCUiHgMyrHVYQqnQbGdsAV0aTad6nZxbOr6w3QjKn1mdQS3Kyzvc+I0xMjZ9yIyMUWHSooHgZ0l7nOng==",
+      "version": "4.0.1",
+      "resolved": "https://registry.npmjs.org/@fastify/express/-/express-4.0.1.tgz",
+      "integrity": "sha512-mEQ6pawaENeZ3swqVtkxdLi8NQC5eKBkclE+7ma1qQMuB+yI6WxDyEp55pdbqPIqBQTN/cGgHv84qxVS7NKC2Q==",
       "dev": true,
       "requires": {
-        "express": "^4.17.1",
-        "fastify-plugin": "^4.0.0"
+        "express": "^4.18.3",
+        "fastify-plugin": "^5.0.0"
       }
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     "@fastify/fast-json-stringify-compiler": {
@@ -47785,7 +47785,7 @@
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       "version": "file:plugins/node/opentelemetry-instrumentation-fastify",
       "requires": {
-        "@fastify/express": "^3.0.0",
+        "@fastify/express": "^4.0.0",
         "@opentelemetry/api": "^1.3.0",
         "@opentelemetry/context-async-hooks": "^1.8.0",
         "@opentelemetry/contrib-test-utils": "^0.45.0",
@@ -57665,9 +57665,9 @@
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-      "resolved": "https://registry.npmjs.org/fastify-plugin/-/fastify-plugin-4.5.1.tgz",
-      "integrity": "sha512-stRHYGeuqpEZTL1Ef0Ovr2ltazUT9g844X5z/zEBFLG8RYlpDiOCIG+ATvYEp+/zmc7sN29mcIMp8gvYplYPIQ==",
+      "version": "5.0.1",
+      "resolved": "https://registry.npmjs.org/fastify-plugin/-/fastify-plugin-5.0.1.tgz",
+      "integrity": "sha512-HCxs+YnRaWzCl+cWRYFnHmeRFyR5GVnJTAaCJQiYzQSDwK9MgJdyAsuL3nh0EWRCYMgQ5MeziymvmAhUHYHDUQ==",
       "dev": true
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     "fastq": {
diff --git a/plugins/node/opentelemetry-instrumentation-fastify/package.json b/plugins/node/opentelemetry-instrumentation-fastify/package.json
index dade9ea581..e35386b4ab 100644
--- a/plugins/node/opentelemetry-instrumentation-fastify/package.json
+++ b/plugins/node/opentelemetry-instrumentation-fastify/package.json
@@ -43,7 +43,7 @@
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   },
   "devDependencies": {
-    "@fastify/express": "^3.0.0",
+    "@fastify/express": "^4.0.0",
     "@opentelemetry/api": "^1.3.0",
     "@opentelemetry/context-async-hooks": "^1.8.0",
     "@opentelemetry/contrib-test-utils": "^0.45.0",