diff --git a/osu.Framework.Tests/Dependencies/Reflection/DependencyContainerTest.cs b/osu.Framework.Tests/Dependencies/Reflection/DependencyContainerTest.cs
index 4bee79d3ed..924f6532d5 100644
--- a/osu.Framework.Tests/Dependencies/Reflection/DependencyContainerTest.cs
+++ b/osu.Framework.Tests/Dependencies/Reflection/DependencyContainerTest.cs
@@ -301,10 +301,7 @@ public void TestDependenciesOverrideParent(string name, Type parent)
             dependencies = new DependencyContainer(dependencies);
             dependencies.CacheAs(2, info);
 
-            Assert.Multiple(() =>
-            {
-                Assert.AreEqual(2, dependencies.Get<int>(info));
-            });
+            Assert.Multiple(() => { Assert.AreEqual(2, dependencies.Get<int>(info)); });
         }
 
         [Test]
@@ -333,8 +330,19 @@ public void TestResolveNullStruct()
             Assert.That(new DependencyContainer().Get<CancellationToken?>(), Is.Null);
         }
 
+        [Test]
+        public void TestModifyBoxedStruct()
+        {
+            var dependencies = new DependencyContainer();
+            dependencies.CacheAs<IBaseInterface>(new BaseStructObject { TestValue = 1 });
+            dependencies.Get<IBaseInterface>().TestValue = 2;
+
+            Assert.That(dependencies.Get<IBaseInterface>().TestValue, Is.EqualTo(2));
+        }
+
         private interface IBaseInterface
         {
+            int TestValue { get; set; }
         }
 
         private class BaseObject
@@ -344,6 +352,7 @@ private class BaseObject
 
         private struct BaseStructObject : IBaseInterface
         {
+            public int TestValue { get; set; }
         }
 
         private class DerivedObject : BaseObject
diff --git a/osu.Framework.Tests/Dependencies/SourceGeneration/DependencyContainerTest.cs b/osu.Framework.Tests/Dependencies/SourceGeneration/DependencyContainerTest.cs
index 9aaa9355e5..30ed15d9db 100644
--- a/osu.Framework.Tests/Dependencies/SourceGeneration/DependencyContainerTest.cs
+++ b/osu.Framework.Tests/Dependencies/SourceGeneration/DependencyContainerTest.cs
@@ -304,10 +304,7 @@ public void TestDependenciesOverrideParent(string name, Type parent)
             dependencies = new DependencyContainer(dependencies);
             dependencies.CacheAs(2, info);
 
-            Assert.Multiple(() =>
-            {
-                Assert.AreEqual(2, dependencies.Get<int>(info));
-            });
+            Assert.Multiple(() => { Assert.AreEqual(2, dependencies.Get<int>(info)); });
         }
 
         [Test]
@@ -336,8 +333,19 @@ public void TestResolveNullStruct()
             Assert.That(new DependencyContainer().Get<CancellationToken?>(), Is.Null);
         }
 
+        [Test]
+        public void TestModifyBoxedStruct()
+        {
+            var dependencies = new DependencyContainer();
+            dependencies.CacheAs<IBaseInterface>(new BaseStructObject { TestValue = 1 });
+            dependencies.Get<IBaseInterface>().TestValue = 2;
+
+            Assert.That(dependencies.Get<IBaseInterface>().TestValue, Is.EqualTo(2));
+        }
+
         private interface IBaseInterface
         {
+            int TestValue { get; set; }
         }
 
         private class BaseObject
@@ -347,6 +355,7 @@ private class BaseObject
 
         private struct BaseStructObject : IBaseInterface
         {
+            public int TestValue { get; set; }
         }
 
         private class DerivedObject : BaseObject
diff --git a/osu.Framework/Allocation/DependencyContainer.cs b/osu.Framework/Allocation/DependencyContainer.cs
index 10da5b4495..30a77fb412 100644
--- a/osu.Framework/Allocation/DependencyContainer.cs
+++ b/osu.Framework/Allocation/DependencyContainer.cs
@@ -44,11 +44,29 @@ public void Cache(object instance, CacheInfo info)
             CacheAs(instance.GetType(), info, instance);
         }
 
+        /// <summary>
+        /// Caches an instance of a type as its most derived type. This instance will be returned each time you <see cref="Get{T}()"/>.
+        /// </summary>
+        /// <param name="instance">The instance to cache.</param>
+        public void Cache<T>(T instance)
+            where T : notnull
+            => Cache(instance, default);
+
+        /// <summary>
+        /// Caches an instance of a type as its most derived type. This instance will be returned each time you <see cref="Get{T}()"/>.
+        /// </summary>
+        /// <param name="instance">The instance to cache.</param>
+        /// <param name="info">Extra information to identify <paramref name="instance"/> in the cache.</param>
+        public void Cache<T>(T instance, CacheInfo info)
+            where T : notnull
+            => CacheAs(instance.GetType(), info, instance);
+
         /// <summary>
         /// Caches an instance of a type as a type of <typeparamref name="T"/>. This instance will be returned each time you <see cref="Get{T}()"/>.
         /// </summary>
         /// <param name="instance">The instance to cache. Must be or derive from <typeparamref name="T"/>.</param>
         public void CacheAs<T>(T instance)
+            where T : notnull
             => CacheAs(instance, default);
 
         /// <summary>
@@ -57,6 +75,7 @@ public void CacheAs<T>(T instance)
         /// <param name="instance">The instance to cache. Must be or derive from <typeparamref name="T"/>.</param>
         /// <param name="info">Extra information to identify <paramref name="instance"/> in the cache.</param>
         public void CacheAs<T>(T instance, CacheInfo info)
+            where T : notnull
             => CacheAs(typeof(T), info, instance);
 
         /// <summary>
@@ -65,6 +84,7 @@ public void CacheAs<T>(T instance, CacheInfo info)
         /// <param name="type">The type to cache <paramref name="instance"/> as.</param>
         /// <param name="instance">The instance to cache. Must be or derive from <paramref name="type"/>.</param>
         public void CacheAs<T>(Type type, T instance)
+            where T : notnull
             => CacheAs(type, instance, default);
 
         /// <summary>
@@ -74,6 +94,7 @@ public void CacheAs<T>(Type type, T instance)
         /// <param name="instance">The instance to cache. Must be or derive from <paramref name="type"/>.</param>
         /// <param name="info">Extra information to identify <paramref name="instance"/> in the cache.</param>
         public void CacheAs<T>(Type type, T instance, CacheInfo info)
+            where T : notnull
             => CacheAs(type, info, instance);
 
         /// <summary>