diff --git a/charts/prometheus-node-exporter/Chart.yaml b/charts/prometheus-node-exporter/Chart.yaml
index 1a45e554d74d..0f5a9a25aa00 100644
--- a/charts/prometheus-node-exporter/Chart.yaml
+++ b/charts/prometheus-node-exporter/Chart.yaml
@@ -6,7 +6,7 @@ keywords:
   - prometheus
   - exporter
 type: application
-version: 4.42.0
+version: 4.42.1
 appVersion: 1.8.2
 home: https://github.com/prometheus/node_exporter/
 sources:
diff --git a/charts/prometheus-node-exporter/templates/_helpers.tpl b/charts/prometheus-node-exporter/templates/_helpers.tpl
index 6f6518b71977..890c487a8f50 100644
--- a/charts/prometheus-node-exporter/templates/_helpers.tpl
+++ b/charts/prometheus-node-exporter/templates/_helpers.tpl
@@ -200,3 +200,38 @@ labelValueLengthLimit: {{ . }}
 {{- end }}
 {{- end }}
 {{- end }}
+
+{{/*
+The default node affinity to exclude 
+- AWS Fargate 
+- Azure virtual nodes
+*/}}
+{{- define "prometheus-node-exporter.defaultAffinity" -}}
+nodeAffinity:
+  requiredDuringSchedulingIgnoredDuringExecution:
+    nodeSelectorTerms:
+    - matchExpressions:
+      - key: eks.amazonaws.com/compute-type
+        operator: NotIn
+        values:
+        - fargate
+      - key: type
+        operator: NotIn
+        values:
+        - virtual-kubelet
+{{- end -}}
+{{- define "prometheus-node-exporter.mergedAffinities" -}}
+{{- $defaultAffinity := include "prometheus-node-exporter.defaultAffinity" . | fromYaml -}}
+{{- with .Values.affinity -}}
+  {{- if .nodeAffinity -}}
+    {{- $_ := set $defaultAffinity "nodeAffinity" (mergeOverwrite $defaultAffinity.nodeAffinity .nodeAffinity) -}}
+  {{- end -}}
+  {{- if .podAffinity -}}
+    {{- $_ := set $defaultAffinity "podAffinity" .podAffinity -}}
+  {{- end -}}
+  {{- if .podAntiAffinity -}}
+    {{- $_ := set $defaultAffinity "podAntiAffinity" .podAntiAffinity -}}
+  {{- end -}}
+{{- end -}}
+{{- toYaml $defaultAffinity -}}
+{{- end -}}
diff --git a/charts/prometheus-node-exporter/templates/daemonset.yaml b/charts/prometheus-node-exporter/templates/daemonset.yaml
index 14030b041338..e3ac2f184381 100644
--- a/charts/prometheus-node-exporter/templates/daemonset.yaml
+++ b/charts/prometheus-node-exporter/templates/daemonset.yaml
@@ -267,10 +267,8 @@ spec:
       hostNetwork: {{ .Values.hostNetwork }}
       hostPID: {{ .Values.hostPID }}
       hostIPC: {{ .Values.hostIPC }}
-      {{- with .Values.affinity }}
       affinity:
-        {{- toYaml . | nindent 8 }}
-      {{- end }}
+        {{- include "prometheus-node-exporter.mergedAffinities" . | nindent 8 }}
       {{- with .Values.dnsConfig }}
       dnsConfig:
         {{- toYaml . | nindent 8 }}