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integration of several multiome datasets #1801

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mengm5 opened this issue Oct 10, 2024 · 0 comments

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mengm5 commented Oct 10, 2024 •

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Hi,
I have 4 10X-multiome (scATAC+scRNA) samples.
How can I integrate them?

Workflow 1

merge 4 scATACs as vignette: https://stuartlab.org/signac/articles/merging
integrate 4 scRNAs as vignette: https://satijalab.org/seurat/articles/integration_introduction
joint scATACs and scRNAs as vignette: https://stuartlab.org/signac/articles/pbmc_multiomic
or vignette: https://stuartlab.org/signac/articles/integrate_atac

Workflow 2

joint scATAC and scRNA of each sample to scMultiome as vignette: https://stuartlab.org/signac/articles/pbmc_multiomic
integrate 4 samples' scMultiome as vignette: https://stuartlab.org/signac/articles/integrate_atac

Which one to choose?

Best
Meng

mengm5 added the documentation label

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