diff --git a/azure-pipelines.yml b/azure-pipelines.yml
index af2907dc9..7bc38e685 100644
--- a/azure-pipelines.yml
+++ b/azure-pipelines.yml
@@ -13,19 +13,17 @@ jobs:
           PYTHON_VERSION: 3.9
     steps:
       - script: bash ci/build_unix.sh
-  # We could not get the OSX CIs to pass easily.
-  # https://github.com/ukoethe/vigra/issues/535
-  # - job: OSX
-  #   pool:
-  #     vmImage: macOS-latest
-  #   strategy:
-  #     matrix:
-  #       py37:
-  #         PYTHON_VERSION: 3.7
-  #   steps:
-  #     - script: |
-  #         sudo xcode-select -s /Applications/Xcode_13.2.1.app
-  #         bash ci/build_unix.sh
+  - job: OSX
+    pool:
+      vmImage: macOS-latest
+    strategy:
+      matrix:
+        py37:
+          PYTHON_VERSION: 3.7
+    steps:
+      - script: |
+          sudo xcode-select -s /Applications/Xcode_13.2.1.app
+          bash ci/build_unix.sh
   - job: Windows
     pool:
       vmImage: windows-2019
diff --git a/ci/build_unix.sh b/ci/build_unix.sh
index 7c46618d8..f1ab30173 100644
--- a/ci/build_unix.sh
+++ b/ci/build_unix.sh
@@ -11,7 +11,15 @@ conda create \
     python=${PYTHON_VERSION} c-compiler cxx-compiler \
     zlib jpeg libpng libtiff hdf5 fftw \
     boost boost-cpp numpy h5py nose sphinx \
-    openexr lemon
+    openexr lemon cmake make
+
+if [[ `uname` == 'Darwin' ]];
+then
+    export SHLIB_EXT=".dylib"
+    export LDFLAGS="-undefined dynamic_lookup ${LDFLAGS}"
+else
+    export SHLIB_EXT=".so"
+fi
 
 source $CONDA/bin/activate vigra
 
@@ -27,7 +35,15 @@ cmake .. \
     -DTEST_VIGRANUMPY=ON \
     -DWITH_OPENEXR=ON \
     -DWITH_LEMON=ON \
-    -DAUTOEXEC_TESTS=OFF
+    -DAUTOEXEC_TESTS=OFF \
+    -DCMAKE_FIND_FRAMEWORK=LAST \
+    -DCMAKE_FIND_APPBUNDLE=LAST \
+    -DZLIB_INCLUDE_DIR=${CONDA_PREFIX}/include \
+    -DZLIB_LIBRARY=${CONDA_PREFIX}/lib/libz${SHLIB_EXT} \
+\
+    -DPNG_LIBRARY=${CONDA_PREFIX}/lib/libpng${SHLIB_EXT} \
+    -DPNG_PNG_INCLUDE_DIR=${CONDA_PREFIX}/include
+
 
 make -j2
 make check -j2
diff --git a/config/FindVIGRANUMPY_DEPENDENCIES.cmake b/config/FindVIGRANUMPY_DEPENDENCIES.cmake
index 1564a18e9..964ae9230 100644
--- a/config/FindVIGRANUMPY_DEPENDENCIES.cmake
+++ b/config/FindVIGRANUMPY_DEPENDENCIES.cmake
@@ -149,7 +149,13 @@ IF(Python_Interpreter_FOUND)
     SET(VIGRANUMPY_INCLUDE_DIRS ${VIGRANUMPY_INCLUDE_DIRS}
         CACHE PATH "include directories needed by VIGRA Python bindings"
         FORCE)
-    SET(VIGRANUMPY_LIBRARIES ${Python_LIBRARIES} ${Boost_PYTHON_LIBRARY})
+    # due to some static linking in Python on conda-forge, Python cannot be directly linked to
+    # see also https://github.com/ukoethe/vigra/pull/538
+    IF(APPLE AND DEFINED ENV{CONDA_TOOLCHAIN_BUILD})
+        SET(VIGRANUMPY_LIBRARIES ${Boost_PYTHON_LIBRARY})
+    ELSE()
+        SET(VIGRANUMPY_LIBRARIES ${Python_LIBRARIES} ${Boost_PYTHON_LIBRARY})
+    ENDIF()
 
     if(TEST_VIGRANUMPY AND NOT VIGRANUMPY_DEPENDENCIES_FOUND)
         MESSAGE(FATAL_ERROR "  vigranumpy dependencies NOT found while TEST_VIGRANUMPY=1")
diff --git a/config/run_test.sh.in b/config/run_test.sh.in
index 9e95ef381..5fa61cf54 100644
--- a/config/run_test.sh.in
+++ b/config/run_test.sh.in
@@ -1 +1,2 @@
+#!/bin/bash
 PATH=@EXTRA_PATH@$PATH && cd @CMAKE_CURRENT_BINARY_DIR@ && (@VIGRA_TEST_EXECUTABLE@ || { touch testsuccess.cxx; exit 1; } )