diff --git a/.github/workflows/build-and-test.yml b/.github/workflows/build-and-test.yml
index 2608ab6b..5f01af23 100644
--- a/.github/workflows/build-and-test.yml
+++ b/.github/workflows/build-and-test.yml
@@ -29,6 +29,16 @@ jobs:
         local-packages:
           - zarr.opam
 
+    env:
+      AWS_ACCESS_KEY_ID: minioadmin
+      AWS_SECRET_ACCESS_KEY: minioadmin
+
+    services:
+      minio:
+        image: fclairamb/minio-github-actions
+        ports:
+          - 9000:9000
+
     name: Ocaml version - ${{ matrix.ocaml-compiler }} - ${{ matrix.os }}
     steps:
       - name: checkout
@@ -36,6 +46,24 @@ jobs:
         with:
           fetch-depth: 2
 
+      - name: Setup Minio
+        run: |
+          mkdir ~/.aws
+          echo '[default]' > ~/.aws/credentials
+          echo 'aws_access_key_id = minioadmin' >> ~/.aws/credentials
+          echo 'aws_secret_access_key = minioadmin' >> ~/.aws/credentials
+          pip3 install minio
+          python3 - <<'EOF'
+          from minio import Minio
+          minio = Minio(
+             'localhost:9000',
+             access_key='minioadmin',
+             secret_key='minioadmin',
+             secure=False
+          )
+          minio.make_bucket('test-bucket-lwt', location='us-east-1')
+          EOF
+
       - name: setup-ocaml
         uses: ocaml/setup-ocaml@v3
         with:
@@ -45,7 +73,7 @@ jobs:
         run: |
           opam install --deps-only --with-test --with-doc --yes zarr
           opam install bytesrw conf-zlib conf-zstd --yes
-          opam install lwt --yes
+          opam install lwt aws-s3-lwt --yes
           opam exec -- dune build zarr zarr-sync zarr-lwt
       
       - name: setup ocaml-5-specific
diff --git a/Makefile b/Makefile
index 1ca1b2a2..5319f402 100644
--- a/Makefile
+++ b/Makefile
@@ -26,3 +26,8 @@ docs:
 .PHONY: view-docs
 view-docs: docs
 	chromium _build/default/_doc/_html/index.html 
+
+.PHONY: minio
+minio:
+	mkdir -p /tmp/minio/test-bucket-lwt
+	docker run --rm -it -p 9000:9000 -v /tmp/minio:/minio minio/minio:latest server /minio
diff --git a/dune-project b/dune-project
index aaa4c9e0..7232da60 100644
--- a/dune-project
+++ b/dune-project
@@ -63,6 +63,7 @@
      (and (>= 4.14.0)))
    (zarr (= :version))
    (lwt (>= 2.5.1))
+   (aws-s3-lwt (>= 4.8.1))
    (odoc :with-doc)
    (ounit2 :with-test)
    (ppx_deriving :with-test)
diff --git a/zarr-lwt.opam b/zarr-lwt.opam
index 4e14ce44..f5e43a41 100644
--- a/zarr-lwt.opam
+++ b/zarr-lwt.opam
@@ -13,6 +13,7 @@ depends: [
   "ocaml" {>= "4.14.0"}
   "zarr" {= version}
   "lwt" {>= "2.5.1"}
+  "aws-s3-lwt" {>= "4.8.1"}
   "odoc" {with-doc}
   "ounit2" {with-test}
   "ppx_deriving" {with-test}
diff --git a/zarr-lwt/src/dune b/zarr-lwt/src/dune
index 459c8244..9df95697 100644
--- a/zarr-lwt/src/dune
+++ b/zarr-lwt/src/dune
@@ -3,6 +3,7 @@
  (public_name zarr-lwt)
  (libraries
    zarr
+   aws-s3-lwt
    lwt
    lwt.unix)
  (ocamlopt_flags
diff --git a/zarr-lwt/src/storage.ml b/zarr-lwt/src/storage.ml
index 8d8bf563..271f613a 100644
--- a/zarr-lwt/src/storage.ml
+++ b/zarr-lwt/src/storage.ml
@@ -163,3 +163,177 @@ module FilesystemStore = struct
 
   include Zarr.Storage.Make(IO)
 end
+
+module AmazonS3Store = struct
+  module Credentials = Aws_s3_lwt.Credentials
+  module S3 = Aws_s3_lwt.S3
+
+  open Deferred.Infix
+  open Deferred.Syntax
+
+  exception S3_error of S3.error
+
+  let empty_content () = S3.{
+    storage_class = Standard;
+    meta_headers = None;
+    etag = String.empty;
+    key = String.empty;
+    last_modified = 0.;
+    size = 0
+  }
+
+  let fold_or_catch ~not_found res =
+    let return_or_raise r () = match r with
+      | Ok v -> Deferred.return v
+      | Error e -> raise (S3_error e)
+    and on_exception ~not_found = function
+      | S3_error S3.Not_found -> Lwt.return (not_found ())
+      | exn -> raise exn
+    in
+    Lwt.catch (return_or_raise res) (on_exception ~not_found)
+
+  let raise_not_found k () = raise (Zarr.Storage.Key_not_found k)
+
+  let empty_Ls = Fun.const ([], S3.Ls.Done)
+
+  let fold_continuation ~return ~more = function
+    | S3.Ls.Done -> Deferred.return return
+    | S3.Ls.More continuation ->
+      continuation () >>= fold_or_catch ~not_found:empty_Ls >>= fun (xs, cont) ->
+      more xs cont
+
+  module IO = struct
+    module Deferred = Deferred
+
+    type t =
+      {retries : int
+      ;bucket : string
+      ;cred : Credentials.t
+      ;endpoint : Aws_s3.Region.endpoint}
+
+    let size t key =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.head ~bucket ~credentials ~key ~endpoint () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      let+ c = fold_or_catch ~not_found:empty_content res in
+      c.size
+
+    let is_member t key =
+      let+ size = size t key in
+      if size = 0 then false else true
+
+    let get t key =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.get ~bucket ~credentials ~endpoint ~key () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      fold_or_catch ~not_found:(raise_not_found key) res
+
+    let get_partial_values t key ranges =
+      let read_range t key (ofs, len) =
+        let range = match len with
+          | None -> S3.{first = Some ofs; last = None}
+          | Some l -> S3.{first = Some ofs; last = Some (ofs + l - 1)}
+        in
+        let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+        let f ~endpoint () = S3.get ~bucket ~credentials ~endpoint ~range ~key () in
+        let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+        let+ data = fold_or_catch ~not_found:(raise_not_found key) res in
+        [data]
+      in
+      Deferred.concat_map (read_range t key) ranges
+
+    let set t key data =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.put ~bucket ~credentials ~endpoint ~data ~key () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      let* _ = fold_or_catch ~not_found:(Fun.const String.empty) res in
+      Deferred.return_unit
+
+    let set_partial_values t key ?(append=false) rsv =
+      let* size = size t key in
+      let* ov = match size with
+        | 0 -> Deferred.return String.empty
+        | _ -> get t key
+      in
+      let f = if append || ov = String.empty then
+        fun acc (_, v) -> acc ^ v else
+        fun acc (rs, v) ->
+          let s = Bytes.unsafe_of_string acc in
+          Bytes.blit_string v 0 s rs String.(length v);
+          Bytes.unsafe_to_string s
+      in
+      set t key (List.fold_left f ov rsv)
+
+    let erase t key =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.delete ~bucket ~credentials ~endpoint ~key () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      fold_or_catch ~not_found:(Fun.const ()) res
+
+    let rec delete_keys t cont () = 
+      let del t xs c = Deferred.iter (delete_content t) xs >>= delete_keys t c in
+      fold_continuation ~return:() ~more:(del t) cont
+
+    and delete_content t S3.{key; _} = erase t key
+
+    and erase_prefix t prefix =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.ls ~bucket ~credentials ~endpoint ~prefix () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      let* xs, rest = fold_or_catch ~not_found:empty_Ls res in
+      Deferred.iter (delete_content t) xs >>= delete_keys t rest
+
+    let rec list t =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.ls ~bucket ~credentials ~endpoint () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      let* xs, rest = fold_or_catch ~not_found:empty_Ls res in
+      accumulate_keys (List.map content_key xs) rest
+
+    and content_key S3.{key; _} = key
+
+    and accumulate_keys acc cont =
+      let append acc xs c = accumulate_keys (acc @ List.map content_key xs) c in
+      fold_continuation ~return:acc ~more:(append acc) cont
+
+    module S = Set.Make(String)
+
+    let rec partition_keys prefix ((l, r) as acc) cont =
+      let split ~acc ~prefix xs c = partition_keys prefix (List.fold_left (add prefix) acc xs) c in
+      fold_continuation ~return:(l, S.elements r) ~more:(split ~acc ~prefix) cont
+
+    and add prefix (l, r) (c : S3.content) =
+      let size = String.length prefix in
+      if not (String.contains_from c.key size '/') then c.key :: l, r else
+      l, S.add String.(sub c.key 0 @@ 1 + index_from c.key size '/') r
+
+    and list_dir t prefix =
+      let bucket = t.bucket and credentials = t.cred and endpoint = t.endpoint in
+      let f ~endpoint () = S3.ls ~bucket ~credentials ~endpoint ~prefix () in
+      let* res = S3.retry ~retries:t.retries ~endpoint ~f () in
+      let* xs, rest = fold_or_catch ~not_found:empty_Ls res in
+      let init = List.fold_left (add prefix) ([], S.empty) xs in
+      partition_keys prefix init rest
+
+    let rec rename t prefix new_prefix =
+      let upload t (k, v) = set t k v in
+      let* xs = list t in
+      let to_delete = List.filter (String.starts_with ~prefix) xs in
+      let* data = Deferred.fold_left (rename_and_add ~t ~prefix ~new_prefix) [] to_delete in
+      let* () = Deferred.iter (upload t) data in
+      Deferred.iter (erase t) to_delete
+
+    and rename_and_add ~t ~prefix ~new_prefix acc k =
+      let l = String.length prefix in
+      let k' = new_prefix ^ String.sub k l (String.length k - l) in
+      let+ a = get t k in (k', a) :: acc
+  end
+
+  let with_open ?(scheme=`Http) ?(inet=`V4) ?(retries=3) ~region ~bucket ~profile f =
+    let* res = Credentials.Helper.get_credentials ~profile () in
+    let cred = Result.fold ~ok:Fun.id ~error:raise res in
+    let endpoint = Aws_s3.Region.endpoint ~inet ~scheme region in
+    f IO.{bucket; cred; endpoint; retries}
+
+  include Zarr.Storage.Make(IO)
+end
diff --git a/zarr-lwt/src/storage.mli b/zarr-lwt/src/storage.mli
index fc8eed67..8296e72f 100644
--- a/zarr-lwt/src/storage.mli
+++ b/zarr-lwt/src/storage.mli
@@ -20,3 +20,35 @@ module FilesystemStore : sig
 
       @raise Failure if [dir] is not a Zarr store path. *)
 end
+
+(** An Lwt-aware Amazon S3 bucket storage backend for a Zarr V3 hierarchy. *)
+module AmazonS3Store : sig
+  exception S3_error of Aws_s3_lwt.S3.error
+
+  include Zarr.Storage.STORE with module Deferred = Deferred
+
+  val with_open :
+    ?scheme:[ `Http | `Https ] ->
+    ?inet:[ `V4 | `V6 ] ->
+    ?retries:int ->
+    region:Aws_s3.Region.t ->
+    bucket:string ->
+    profile:string ->
+    (t -> 'a Lwt.t) ->
+    'a Lwt.t
+  (** [with_open ~region ~bucket ~profile f] opens an S3 bucket store with
+      bucket name [bucket] at region [region] using credentials specified by
+      profile [profile]. The credentials are read locally from a [~/.aws/credentials]
+      file or from an IAM service if the profile or file is not available.
+      Function [f] is applied to the store's open handle and its output is
+      returned to the caller.
+
+      {ul 
+      {- [scheme] is the HTTP scheme to use when connecting to S3, and must be
+        one of [`Http | `Https]. Defaults to [`Http].}
+      {- [inet] is the IP version and must be one of [`V4 | `V6]. Defaults to [`V4].}
+      {- [retries] is the number of times to retry a request should it return an error.}
+      }
+
+      @raise S3_error if an error occurs while sending a request to the S3 service. *)
+end
diff --git a/zarr-lwt/test/test_lwt.ml b/zarr-lwt/test/test_lwt.ml
index e3bf3f98..cf0b8932 100644
--- a/zarr-lwt/test/test_lwt.ml
+++ b/zarr-lwt/test/test_lwt.ml
@@ -141,11 +141,18 @@ let _ =
         (Zarr.Storage.Not_a_filesystem_store fn)
         (fun () -> FilesystemStore.open_store fn);
 
+      (* ZipStore configuration *)
       let zpath = tmp_dir ^ ".zip" in
+      (* AmazonS3Store configuration *)
+      let region = Aws_s3.Region.minio ~port:9000 ~host:"localhost" ()
+      and bucket = "test-bucket-lwt"
+      and profile = "default" in
+
       Lwt_main.run @@ Lwt.join 
         [ZipStore.with_open `Read_write zpath (fun z -> test_storage (module ZipStore) z)
          (* test just opening the now exisitant archive created by the previous test. *)
         ;ZipStore.with_open `Read_only zpath (fun _ -> ZipStore.Deferred.return_unit)
+        ;AmazonS3Store.with_open ~region ~bucket ~profile (test_storage (module AmazonS3Store))
         ;test_storage (module MemoryStore) @@ MemoryStore.create ()
         ;test_storage (module FilesystemStore) s])
 ])