diff --git a/packages/zowe-explorer/CHANGELOG.md b/packages/zowe-explorer/CHANGELOG.md
index 7ae405eee..95334a77a 100644
--- a/packages/zowe-explorer/CHANGELOG.md
+++ b/packages/zowe-explorer/CHANGELOG.md
@@ -30,7 +30,7 @@ All notable changes to the "vscode-extension-for-zowe" extension will be documen
 - Fixed an issue where data set nodes did not update if migrated or recalled outside of Zowe Explorer. [#3294](https://github.com/zowe/zowe-explorer-vscode/issues/3294)
 - Fixed an issue where listing data sets resulted in an error after opening a data set with an encoding. [#3347](https://github.com/zowe/zowe-explorer-vscode/issues/3347)
 - Fixed an issue where binary USS files were not fetched using the "Pull from Mainframe" context menu option. [#3355](https://github.com/zowe/zowe-explorer-vscode/issues/3355)
-- Fixed an issue where cached encoding was applied for all profiles with the same dataset in the "Open with Encoding" menu. [#3363](https://github.com/zowe/zowe-explorer-vscode/pull/3363)
+- Fixed an issue where cached encoding was applied for all profiles with the same dataset or USS path in the "Open with Encoding" menu. [#3363](https://github.com/zowe/zowe-explorer-vscode/pull/3363)
 
 ## `3.0.3`
 
diff --git a/packages/zowe-explorer/src/trees/shared/SharedUtils.ts b/packages/zowe-explorer/src/trees/shared/SharedUtils.ts
index 9895a58db..463e143d4 100644
--- a/packages/zowe-explorer/src/trees/shared/SharedUtils.ts
+++ b/packages/zowe-explorer/src/trees/shared/SharedUtils.ts
@@ -143,7 +143,7 @@ export class SharedUtils {
     public static async getCachedEncoding(node: IZoweTreeNode): Promise<string | undefined> {
         let cachedEncoding: ZosEncoding;
         if (SharedUtils.isZoweUSSTreeNode(node)) {
-            cachedEncoding = await node.getEncodingInMap(node.fullPath);
+            cachedEncoding = await node.getEncodingInMap(node.resourceUri.path);
         } else {
             cachedEncoding = await (node as IZoweDatasetTreeNode).getEncodingInMap(node.resourceUri.path);
         }
diff --git a/packages/zowe-explorer/src/trees/uss/ZoweUSSNode.ts b/packages/zowe-explorer/src/trees/uss/ZoweUSSNode.ts
index a50d6c341..254479dae 100644
--- a/packages/zowe-explorer/src/trees/uss/ZoweUSSNode.ts
+++ b/packages/zowe-explorer/src/trees/uss/ZoweUSSNode.ts
@@ -299,9 +299,9 @@ export class ZoweUSSNode extends ZoweTreeNode implements IZoweUSSTreeNode {
         }
         UssFSProvider.instance.setEncodingForFile(this.resourceUri, encoding);
         if (encoding != null) {
-            this.updateEncodingInMap(this.fullPath, encoding);
+            this.updateEncodingInMap(this.resourceUri.path, encoding);
         } else {
-            delete UssFSProvider.instance.encodingMap[this.fullPath];
+            delete UssFSProvider.instance.encodingMap[this.resourceUri.path];
         }
         if (this.getParent() && this.getParent().contextValue === Constants.FAV_PROFILE_CONTEXT) {
             this.contextValue =