SpliceSeq is an application that aligns RNASeq reads to models of all human genes. The analysis produces splice graphs annotated with read totals and percent-spliced-in (PSI) values for all potential splice events. SpliceSeq can perform comparative analysis between samples or groups of samples to find significant differences in splicing patterns. The results are presented in a dynamic, graphical interface that allows sorting/filtering of splice events and exploration of splicing changes and the impact on protein product.
Please see the documentation on the MD Anderson BCB website for instructions on installing and running SpliceSeq.