Comparison of gene expression levels in the left and right sides of the developing mouse heart

Repository accompanying the paper Molecular characterization of Left-Right symmetry breaking in the mouse embryo, by Tyser et al. 2023. DOI: 10.1101/2022.12.26.521947

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Data

This study reanalyses data from Tyser, Ibarra-Soria et al., Science, 2021 (DOI: 10.1126/science.abb2986.)

• For details on the primary analysis of the dataset, please visit https://github.com/MarioniLab/mouseHeart_2020.
• To run the scripts, please download data from here.

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Exploring the dataset

The original dataset can be explored dynamically at https://marionilab.cruk.cam.ac.uk/heartAtlas.

• An additional tab [Left-right gene expression] has been added, to plot the expression of any gene in the left and right cells separately.