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Add NB-GLMM to master branch. #295

Merged
merged 315 commits into from
Nov 9, 2023
Merged

Add NB-GLMM to master branch. #295

merged 315 commits into from
Nov 9, 2023

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MikeDMorgan
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This major update to Milo (2.0) introduces a mixed effect model. This can be used to model dependence between observations, including genetic relationships. Therefore, Milo can now be used to identify cell state quantitative trait loci (csQTL). More details are included in https://github.com/MorganResearchLab/Milo2.0Analysis_2023

Merge all Milo-GLMM code into `alice` branch prior to devel.
Introduce Milo NB-GLMM to devel in preparation for manuscript submission.
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Codecov Report

Merging #295 (47fb880) into master (3e4e264) will decrease coverage by 5.96%.
The diff coverage is 50.94%.

❗ Current head 47fb880 differs from pull request most recent head 1633c34. Consider uploading reports for the commit 1633c34 to get more accurate results

Impacted file tree graph

@@            Coverage Diff             @@
##           master     #295      +/-   ##
==========================================
- Coverage   61.65%   55.69%   -5.96%     
==========================================
  Files          19       30      +11     
  Lines        1476     3065    +1589     
==========================================
+ Hits          910     1707     +797     
- Misses        566     1358     +792     
Files Coverage Δ
R/buildGraph.R 61.81% <ø> (ø)
R/findNhoodGroupMarkers.R 68.42% <ø> (ø)
R/graphSpatialFDR.R 72.46% <ø> (+1.03%) ⬆️
R/makeNhoods.R 94.49% <100.00%> (ø)
R/plotNhoods.R 27.04% <ø> (ø)
R/milo.R 66.66% <0.00%> (ø)
R/annotateNhoods.R 91.30% <84.61%> (-3.70%) ⬇️
R/checkSeparation.R 91.66% <91.66%> (ø)
R/utils.R 87.27% <90.90%> (+2.42%) ⬆️
src/invertPseudoVar.cpp 74.07% <74.07%> (ø)
... and 10 more

@MikeDMorgan MikeDMorgan merged commit 51a8e46 into master Nov 9, 2023
5 of 6 checks passed
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5 participants