Demonstrator 3: EHR Population Generalizability (Archived)

Archived topic given it is not of immediate focus

Representativeness and Generalizability of Discoveries in EHR Populations

Approaches we develop with translator datasets may help to discover new risk factors for developing a condition, responding to a treatment, etc. Discoveries made in one population, however, may have limited success when applied to populations other than those that findings were made in. Thus, there is a need to quantify representativeness of data and generalizability of approaches so that we consider such limitations when applying clinically.

• Task 1. Generalizability of clinical trial results for a population (developed by Orange and Red teams) here
• Task 2. Representativeness of condition-specific signs and symptoms in a population here
• Task 3. Representativeness of gene tests in a population