This is a very thin client for the Handle Server Web API. There's really not much to it, it's basically an educational reference implementation for the service, but we're using it, so feel free.
pip install -e git+https://github.com/cordmata/handle-client.git#egg=handle
from handle import Client
client = Client("http://your.server.org/handle-service/", "handleAdmin", "yourPass")
client.create("2286.9/test", "http://example.org")
#>>> http://hdl.handle.net/2286.9/test
client.read("2286.9/test")
#>>> http://example.org
client.update("2286.9/test", "http://new.example.org")
#>>> http://hdl.handle.net/2286.9/test
client.delete("2286.9/test")
Told you...not much to it.