Qt for Python is great, but not as easy to use initially as C++ and Qt Creator, on Python you cannot use .ui files directly from your program without a little work.
I have found two methods of achieving this from Python:
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Google pyside_dynamic.py (https://gist.github.com/cpbotha) and use this to dynamically access your ui files
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convert the ui and resource files a runtime by using pyside2-uic for ui files, and pyside2-rcc for resources respectively.