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MEMDIS (MEMbrane DISorder)

Prediction of disordered regions

in transmembrane proteins

Laszlo Dobson

Institute of Enzymology

2021

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USAGE Main.py [FASTA] [TOPOLOGY] [SURFACE] [PSI-BLAST] [LOW-COMPLEXITY] [MODE] e.g. Main.py test.fas [test.xml/test.top] test.rsa test.psi test.json sens

FASTA Input file must be in fasta format

TOPOLOGY Topology file in CCTOP XML format see: http://cctop.enzim.ttk.mta.hu/?_=/documents/direct_interface.html

SURFACE Surface accessibility file in netsurfp-1.0 format see: http://www.cbs.dtu.dk/services/NetSurfP-1.0/

PSI-BLAST Psi-blast result

MODE Sensitive/Specific prediction [sens/spec]

OUTPUT Number Residue Topology DisorderedScore

DEPENDENCIES

  1. Install Keras and TensorFlow: https://phoenixnap.com/kb/how-to-install-keras-on-linux

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