Efficient encoding of (short) biological sequences. This package ist designed to deal with in-memory snippets of DNA, RNA, and amino acids. The encoding is geared toward time-efficiency, not necessarily space efficiency (we use Int's for encoding characters, not the smallest type possible).
Additional modules provide conversion capabilities between different types of characters according to biological laws, and some biochemical constraint information. The latter includes canonical and non-canonical pairing information for RNA.
Actual energy parameters for pairings are provided by other packages, for example BiobaseTurner for the loop energy model with measured parameters.
Christian Hoener zu Siederdissen
Leipzig University, Leipzig, Germany
[email protected]
http://www.bioinf.uni-leipzig.de/~choener/