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Update Xmod-SIS.Rmd
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smitdave committed Dec 13, 2023
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Expand Up @@ -15,39 +15,41 @@ library(deSolve)
suppressMessages(require(knitr))
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# {.tabset}

## $\odot$

The SIS model, as it is now called, is a simple compartmental model, first introduced by Ross. It is included in `exDE` as a base model.

**Parameters**

+ $r$ is the rate infections clear

+ $b$ is the fraction of bites by infective mosquitoes that transmit parasites and cause an infection.

+ $c$ is the fraction of bites on an infectious human that would infect a mosquito.

**Dynamics**

The model defined herein is defined in two parts. To model exposure and infection (*i.e.* the conversion of eir into foi), we assume that the fraction of infective bites that cause an infection is $b$. The dynamics are given by:

$$
\frac{dX}{dt} = h (H-X)-rX
$$

**Net Infectiousness**

True prevalence is:

$$x = \frac{X}{H}.$$

In our implementation, net infectiousness is linearly proportional to prevalence:

$$c x.$$
In this implementation, there is no immunity, but we assume a constant fraction of all infectious bites cause an infection.

**Parameters**

+ $r$ is the rate infections clear

+ $b$ is the fraction of bites by infective mosquitoes that transmit parasites and cause an infection.

+ $c$ is the fraction of bites on an infectious human that would infect a mosquito.
*Exposure and Infection*

In this model family, there is no immunity. The model assumes that a constant fraction of all infectious bites, $b$, cause an infection.

## $\dagger$

**References**
## References

1. Ross R. Report on the Prevention of Malaria in Mauritius. London: Waterlow; 1908.
2. Ross R. The Prevention of Malaria. 2nd ed. London: John Murray; 1911.
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