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  1. AlexandrovLab/SigProfilerMatrixGenerator AlexandrovLab/SigProfilerMatrixGenerator Public

    SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED fil…

    Python 100 37

  2. AlexandrovLab/SigProfilerPlotting AlexandrovLab/SigProfilerPlotting Public

    SigProfilerPlotting provides a standard tool for displaying all types of mutational signatures as well as all types of mutational patterns in cancer genomes. The tool seamlessly integrates with oth…

    Python 46 13

  3. AlexandrovLab/SigProfilerSimulator AlexandrovLab/SigProfilerSimulator Public

    SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double p…

    Python 18 4

  4. AlexandrovLab/SigProfilerMatrixGeneratorR AlexandrovLab/SigProfilerMatrixGeneratorR Public

    R wrapper for utilizing the SigProfilerMatrixGenerator framework

    R 20 4

  5. AlexandrovLab/SigProfilerPlottingR AlexandrovLab/SigProfilerPlottingR Public

    An R wrapper for running the SigProfilerPlotting framework

    R 10 1

  6. AlexandrovLab/SigProfilerClusters AlexandrovLab/SigProfilerClusters Public

    Tool for analyzing the inter-mutational distances between SNV-SNV and INDEL-INDEL mutations. Tool separates mutations into clustered and non-clustered groups on a sample-dependent basis.

    Python 11 1