Issue 28070 40

[pgaudet]

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[github-actions]

Here's a diff of how these changes impact the classified ontology:

Ontology comparison

Left

• Ontology IRI: http://purl.obolibrary.org/obo/go.owl
• Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-08-30/go.owl
• Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-master.owl/reasoned.owl

Right

• Ontology IRI: http://purl.obolibrary.org/obo/go.owl
• Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-08-30/go.owl
• Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-pr.owl/reasoned.owl

Ontology imports

Ontology annotations

1,4-alpha-oligoglucan phosphorylase activity http://purl.obolibrary.org/obo/GO_0004645

Removed

• 1,4-alpha-oligoglucan phosphorylase activity database_cross_reference "EC:2.4.1.1"

• 1,4-alpha-oligoglucan phosphorylase activity definition "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase."

  • database_cross_reference "EC:2.4.1.1"

• 1,4-alpha-oligoglucan phosphorylase activity database_cross_reference "MetaCyc:RXN-1826"

Added

• 1,4-alpha-oligoglucan phosphorylase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• 1,4-alpha-oligoglucan phosphorylase activity database_cross_reference "EC:2.4.1.1"

  • source "skos:exactMatch"

• 1,4-alpha-oligoglucan phosphorylase activity database_cross_reference "RHEA:41732"

  • source "skos:exactMatch"

• 1,4-alpha-oligoglucan phosphorylase activity database_cross_reference "MetaCyc:RXN0-5184"

• 1,4-alpha-oligoglucan phosphorylase activity definition "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate."

  • database_cross_reference "RHEA:41732"

4-aminobutyrate:2-oxoglutarate transaminase activity http://purl.obolibrary.org/obo/GO_0034386

Removed

• 4-aminobutyrate:2-oxoglutarate transaminase activity database_cross_reference "EC:2.6.1.19"

• 4-aminobutyrate:2-oxoglutarate transaminase activity database_cross_reference "RHEA:23352"

• 4-aminobutyrate:2-oxoglutarate transaminase activity definition "Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate."

  • database_cross_reference "GOC:mah"

  • database_cross_reference "EC:2.6.1.19"

Added

• 4-aminobutyrate:2-oxoglutarate transaminase activity definition "Catalysis of the reaction: 2-oxoglutarate + 4-aminobutanoate = L-glutamate + succinate semialdehyde."

  • database_cross_reference "RHEA:23352"

• 4-aminobutyrate:2-oxoglutarate transaminase activity database_cross_reference "RHEA:23352"

  • source "skos:exactMatch"

• 4-aminobutyrate:2-oxoglutarate transaminase activity database_cross_reference "EC:2.6.1.19"

  • source "skos:exactMatch"

4-aminobutyrate:pyruvate transaminase activity http://purl.obolibrary.org/obo/GO_0034387

Removed

• 4-aminobutyrate:pyruvate transaminase activity database_cross_reference "EC:2.6.1.96"

• 4-aminobutyrate:pyruvate transaminase activity database_cross_reference "RHEA:32263"

• 4-aminobutyrate:pyruvate transaminase activity definition "Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine."

  • database_cross_reference "GOC:mah"

  • database_cross_reference "EC:2.6.1.96"

Added

• 4-aminobutyrate:pyruvate transaminase activity database_cross_reference "RHEA:32263"

  • source "skos:narrowMatch"

• 4-aminobutyrate:pyruvate transaminase activity database_cross_reference "EC:2.6.1.96"

  • source "skos:exactMatch"

• 4-aminobutyrate:pyruvate transaminase activity definition "Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine. Also converts glyoxylate to glycine."

  • database_cross_reference "EC:2.6.1.96"

• 4-aminobutyrate:pyruvate transaminase activity database_cross_reference "RHEA:32267"

  • source "skos:narrowMatch"

D-erythro-sphingosine kinase activity http://purl.obolibrary.org/obo/GO_0017050

Removed

• D-erythro-sphingosine kinase activity database_cross_reference "EC:2.7.1.91"

• D-erythro-sphingosine kinase activity has_exact_synonym "sphingosine kinase activity"

• D-erythro-sphingosine kinase activity database_cross_reference "RHEA:35847"

• D-erythro-sphingosine kinase activity definition "Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP."

  • database_cross_reference "MetaCyc:RXN3DJ-11417"

• D-erythro-sphingosine kinase activity SubClassOf has participant some hydron

• D-erythro-sphingosine kinase activity SubClassOf lipid kinase activity

• D-erythro-sphingosine kinase activity SubClassOf phosphotransferase activity, alcohol group as acceptor

• D-erythro-sphingosine kinase activity SubClassOf has participant some ATP(4-)

• D-erythro-sphingosine kinase activity SubClassOf has participant some ADP(3-)

Added

• D-erythro-sphingosine kinase activity definition "Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP."

  • database_cross_reference "RHEA:35847"

• D-erythro-sphingosine kinase activity database_cross_reference "EC:2.7.1.91"

  • source "skos:broadMatch"

• D-erythro-sphingosine kinase activity database_cross_reference "RHEA:35847"

  • source "skos:exactMatch"

• D-erythro-sphingosine kinase activity has_broad_synonym "sphingosine kinase activity"

• D-erythro-sphingosine kinase activity SubClassOf sphinganine kinase activity

L-glutamine:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0080100

Removed

• L-glutamine:2-oxoglutarate aminotransferase activity comment "This reaction falls within the larger set of reactions associated with EC:2.6.1.50 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.50)."

• L-glutamine:2-oxoglutarate aminotransferase activity database_cross_reference "EC:2.6.1.50"

• L-glutamine:2-oxoglutarate aminotransferase activity definition "Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate."

  • database_cross_reference "PMID:18394996"

• L-glutamine:2-oxoglutarate aminotransferase activity label "L-glutamine:2-oxoglutarate aminotransferase activity"

• L-glutamine:2-oxoglutarate aminotransferase activity SubClassOf L-glutamine aminotransferase activity

Added

• L-glutamine:2-oxoglutarate aminotransferase activity term replaced by "GO:0050362"

• L-glutamine:2-oxoglutarate aminotransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• L-glutamine:2-oxoglutarate aminotransferase activity label "obsolete L-glutamine:2-oxoglutarate aminotransferase activity"

• L-glutamine:2-oxoglutarate aminotransferase activity deprecated true

• L-glutamine:2-oxoglutarate aminotransferase activity definition "OBSOLETE. Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate."

  • database_cross_reference "PMID:18394996"

• L-glutamine:2-oxoglutarate aminotransferase activity comment "This term was obsoleted because it is a specific substrate of L-tryptophan:2-oxoglutarate aminotransferase activity ; GO:0050362."

L-isoleucine transaminase activity http://purl.obolibrary.org/obo/GO_0052656

Removed

• L-isoleucine transaminase activity database_cross_reference "RHEA:24801"

• L-isoleucine transaminase activity definition "Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid."

  • database_cross_reference "MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN"

  • database_cross_reference "EC:2.6.1.42"

Added

• L-isoleucine transaminase activity database_cross_reference "RHEA:24801"

  • source "skos:exactMatch"

• L-isoleucine transaminase activity definition "Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid."

  • database_cross_reference "RHEA:24801"

L-leucine transaminase activity http://purl.obolibrary.org/obo/GO_0052654

Removed

• L-leucine transaminase activity database_cross_reference "EC:2.6.1.42"

SHG alpha-glucan phosphorylase activity http://purl.obolibrary.org/obo/GO_0102499

Removed

• SHG alpha-glucan phosphorylase activity label "SHG alpha-glucan phosphorylase activity"

• SHG alpha-glucan phosphorylase activity database_cross_reference "EC:2.4.1.1"

• SHG alpha-glucan phosphorylase activity database_cross_reference "RHEA:41732"

• SHG alpha-glucan phosphorylase activity database_cross_reference "MetaCyc:RXN-14353"

• SHG alpha-glucan phosphorylase activity definition "Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "RHEA:41732"

• SHG alpha-glucan phosphorylase activity SubClassOf has participant some alpha-D-glucose 1-phosphate(2-)

• SHG alpha-glucan phosphorylase activity SubClassOf has participant some (1->4)-alpha-D-glucan

• SHG alpha-glucan phosphorylase activity SubClassOf hexosyltransferase activity

• SHG alpha-glucan phosphorylase activity SubClassOf has participant some hydrogenphosphate

Added

• SHG alpha-glucan phosphorylase activity comment "This term was obsoleted because it represents a specific substrate of 1,4-alpha-oligoglucan phosphorylase activity ; GO:0004645."

• SHG alpha-glucan phosphorylase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• SHG alpha-glucan phosphorylase activity definition "OBSOLETE. Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan."

  • database_cross_reference "GOC:pz"

• SHG alpha-glucan phosphorylase activity term replaced by "GO:0004645"

• SHG alpha-glucan phosphorylase activity deprecated true

• SHG alpha-glucan phosphorylase activity label "obsolete SHG alpha-glucan phosphorylase activity"

adenine phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0003999

Removed

• adenine phosphoribosyltransferase activity database_cross_reference "RHEA:16609"

• adenine phosphoribosyltransferase activity definition "Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "EC:2.4.2.7"

• adenine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.7"

Added

• adenine phosphoribosyltransferase activity definition "Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "RHEA:16609"

• adenine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.7"

  • source "skos:exactMatch"

• adenine phosphoribosyltransferase activity database_cross_reference "RHEA:16609"

  • source "skos:exactMatch"

agmatine aminopropyltransferase activity http://purl.obolibrary.org/obo/GO_0043919

Removed

• agmatine aminopropyltransferase activity database_cross_reference "EC:2.5.1.104"

• agmatine aminopropyltransferase activity definition "Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine."

  • database_cross_reference "GOC:jl"

  • database_cross_reference "PMID:15983049"

Added

• agmatine aminopropyltransferase activity database_cross_reference "RHEA:36487"

  • source "skos:exactMatch"

• agmatine aminopropyltransferase activity database_cross_reference "EC:2.5.1.104"

  • source "skos:broadMatch"

• agmatine aminopropyltransferase activity definition "Catalysis of the reaction: agmatine + S-adenosyl 3-(methylsulfanyl)propylamine = H+ + N1-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine."

  • database_cross_reference "PMID:15983049"

  • database_cross_reference "RHEA:36487"

• agmatine aminopropyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

baicalein 7-O-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0102159

Removed

• baicalein 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

• baicalein 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28314"

• baicalein 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein = H+ + UDP + baicalin."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.4.1.253"

Added

• baicalein 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28314"

  • source "skos:exactMatch"

• baicalein 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

  • source "skos:broadMatch"

• baicalein 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein = H+ + UDP + baicalin."

  • database_cross_reference "RHEA:28314"

• baicalein 7-O-glucuronosyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

branched-chain-amino-acid transaminase activity http://purl.obolibrary.org/obo/GO_0004084

Removed

• branched-chain-amino-acid transaminase activity database_cross_reference "EC:2.6.1.42"

• branched-chain-amino-acid transaminase activity definition "Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid."

  • database_cross_reference "GOC:mah"

  • database_cross_reference "EC:2.6.1.42"

Added

• branched-chain-amino-acid transaminase activity definition "Catalysis of the reaction: a branched-chain amino acid (L-leucine, L-isoleucine and L-valine) + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid."

  • database_cross_reference "EC:2.6.1.42"

• branched-chain-amino-acid transaminase activity database_cross_reference "EC:2.6.1.42"

  • source "skos:exactMatch"

cadaverine aminopropyltransferase activity http://purl.obolibrary.org/obo/GO_0043918

Removed

• cadaverine aminopropyltransferase activity database_cross_reference "EC:2.5.1.104"

• cadaverine aminopropyltransferase activity definition "Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine."

  • database_cross_reference "GOC:jl"

  • database_cross_reference "PMID:17545282"

Added

• cadaverine aminopropyltransferase activity database_cross_reference "EC:2.5.1.104"

  • source "skos:broadMatch"

• cadaverine aminopropyltransferase activity database_cross_reference "RHEA:33387"

  • source "skos:exactMatch"

• cadaverine aminopropyltransferase activity definition "Catalysis of the reaction: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine = aminopropylcadaverine + H+ + S-methyl-5'-thioadenosine."

  • database_cross_reference "RHEA:33387"

  • database_cross_reference "PMID:17545282"

cellobiose phosphorylase activity http://purl.obolibrary.org/obo/GO_0047738

Removed

• cellobiose phosphorylase activity database_cross_reference "EC:2.4.1.20"

• cellobiose phosphorylase activity definition "Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose."

  • database_cross_reference "EC:2.4.1.20"

  • database_cross_reference "MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN"

• cellobiose phosphorylase activity database_cross_reference "RHEA:19493"

Added

• cellobiose phosphorylase activity database_cross_reference "EC:2.4.1.20"

  • source "skos:exactMatch"

• cellobiose phosphorylase activity database_cross_reference "RHEA:19493"

  • source "skos:exactMatch"

• cellobiose phosphorylase activity definition "Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose."

  • database_cross_reference "RHEA:19493"

ceramide glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0008120

Removed

• ceramide glucosyltransferase activity database_cross_reference "EC:2.4.1.80"

• ceramide glucosyltransferase activity definition "Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine."

  • database_cross_reference "EC:2.4.1.80"

• ceramide glucosyltransferase activity database_cross_reference "RHEA:12088"

Added

• ceramide glucosyltransferase activity definition "Catalysis of the reaction: an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP."

  • database_cross_reference "RHEA:12088"

• ceramide glucosyltransferase activity database_cross_reference "EC:2.4.1.80"

  • source "skos:exactMatch"

• ceramide glucosyltransferase activity database_cross_reference "RHEA:12088"

  • source "skos:exactMatch"

ceramide kinase activity http://purl.obolibrary.org/obo/GO_0001729

Removed

• ceramide kinase activity definition "Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate."
  • database_cross_reference "EC:2.7.1.138"

Added

• ceramide kinase activity definition "Catalysis of the reaction: an N-acylsphing-4-enine + ATP = ADP + an N-acylsphing-4-enine 1-phosphate + H+."
  • database_cross_reference "EC:2.7.1.138"

chitobiose phosphorylase activity http://purl.obolibrary.org/obo/GO_0052756

Removed

• chitobiose phosphorylase activity label "chitobiose phosphorylase activity"

• chitobiose phosphorylase activity definition "Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units."

  • database_cross_reference "PMID:15274915"

  • database_cross_reference "Wikipedia:chitobiose"

  • database_cross_reference "GOC:mengo_curators"

• chitobiose phosphorylase activity SubClassOf 1,4-alpha-oligoglucan phosphorylase activity

Added

• chitobiose phosphorylase activity comment "This term was obsoleted because there is no evidence that this activity exists,"

• chitobiose phosphorylase activity deprecated true

• chitobiose phosphorylase activity definition "OBSOLETE. Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units."

  • database_cross_reference "PMID:15274915"

  • database_cross_reference "Wikipedia:chitobiose"

  • database_cross_reference "GOC:mengo_curators"

• chitobiose phosphorylase activity label "obsolete chitobiose phosphorylase activity"

• chitobiose phosphorylase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

dihydroceramide glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0102769

Removed

• dihydroceramide glucosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine."

  • database_cross_reference "EC:2.4.1.80"

  • database_cross_reference "GOC:pz"

• dihydroceramide glucosyltransferase activity database_cross_reference "MetaCyc:RXN-7793"

• dihydroceramide glucosyltransferase activity database_cross_reference "EC:2.4.1.80"

• dihydroceramide glucosyltransferase activity label "dihydroceramide glucosyltransferase activity"

• dihydroceramide glucosyltransferase activity SubClassOf hexosyltransferase activity

Added

• dihydroceramide glucosyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• dihydroceramide glucosyltransferase activity definition "OBSOLETE. Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine."

  • database_cross_reference "GOC:pz"

• dihydroceramide glucosyltransferase activity label "obsolete dihydroceramide glucosyltransferase activity"

• dihydroceramide glucosyltransferase activity deprecated true

• dihydroceramide glucosyltransferase activity term replaced by "GO:0008120"

• dihydroceramide glucosyltransferase activity comment "This term was obsoleted because it represents a specific substrate of ceramide glucosyltransferase activity ; GO:0008120"

dihydroceramide kinase activity http://purl.obolibrary.org/obo/GO_0102773

Removed

• dihydroceramide kinase activity database_cross_reference "MetaCyc:RXN-7799"

• dihydroceramide kinase activity definition "Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.7.1.138"

• dihydroceramide kinase activity label "dihydroceramide kinase activity"

• dihydroceramide kinase activity database_cross_reference "EC:2.7.1.138"

• dihydroceramide kinase activity SubClassOf phosphotransferase activity, alcohol group as acceptor

Added

• dihydroceramide kinase activity comment "This term was obsoleted because it represents a specific susbtrate of ceramide kinase activity ; GO:0001729."

• dihydroceramide kinase activity term replaced by "GO:0001729"

• dihydroceramide kinase activity definition "OBSOLETE. Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate."

  • database_cross_reference "GOC:pz"

• dihydroceramide kinase activity label "obsolete dihydroceramide kinase activity"

• dihydroceramide kinase activity deprecated true

• dihydroceramide kinase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

gamma-aminobutyrate transaminase (glyoxylate dependent) activity http://purl.obolibrary.org/obo/GO_0102351

Removed

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity database_cross_reference "EC:2.6.1.96"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity label "gamma-aminobutyrate transaminase (glyoxylate dependent) activity"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity database_cross_reference "MetaCyc:RXN-13328"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity database_cross_reference "RHEA:32267"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity definition "Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.6.1.96"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity SubClassOf has participant some 4-oxobutanoate

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity SubClassOf has participant some glycine zwitterion

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity SubClassOf transaminase activity

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity SubClassOf has participant some glyoxylate

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity SubClassOf has participant some gamma-aminobutyric acid zwitterion

Added

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity term replaced by "GO:0034387"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity definition "OBSOLETE. Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine."

  • database_cross_reference "GOC:pz"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity comment "This term was obsoleted because it represents a specific substrate of 4-aminobutyrate:pyruvate transaminase activity ; GO:0034387."

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity deprecated true

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity label "obsolete gamma-aminobutyrate transaminase (glyoxylate dependent) activity"

• gamma-aminobutyrate transaminase (glyoxylate dependent) activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

glycogen phosphorylase activity http://purl.obolibrary.org/obo/GO_0008184

Removed

• glycogen phosphorylase activity definition "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate."

  • database_cross_reference "MetaCyc:GLYCOPHOSPHORYL-RXN"

  • database_cross_reference "EC:2.4.1.1"

• glycogen phosphorylase activity database_cross_reference "MetaCyc:GLYCOPHOSPHORYL-RXN"

Added

• glycogen phosphorylase activity database_cross_reference "MetaCyc:GLYCOPHOSPHORYL-RXN"

  • source "skos:exactMatch"

• glycogen phosphorylase activity database_cross_reference "EC:2.4.1.1"

  • source "skos:broadMatch"

• glycogen phosphorylase activity definition "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate."

  • database_cross_reference "MetaCyc:GLYCOPHOSPHORYL-RXN"

guanine phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0052657

Removed

• guanine phosphoribosyltransferase activity definition "Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "GOC:curators"

  • database_cross_reference "EC:2.4.2.8"

• guanine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.8"

• guanine phosphoribosyltransferase activity database_cross_reference "RHEA:25424"

Added

• guanine phosphoribosyltransferase activity database_cross_reference "RHEA:25424"

  • source "skos:exactMatch"

• guanine phosphoribosyltransferase activity definition "Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "RHEA:25424"

• guanine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.8"

  • source "skos:broadMatch"

guanosine kinase activity http://purl.obolibrary.org/obo/GO_0106366

Removed

• guanosine kinase activity database_cross_reference "RHEA:27710"

• guanosine kinase activity database_cross_reference "EC:2.7.1.73"

Added

• guanosine kinase activity database_cross_reference "RHEA:27710"

  • source "skos:exactMatch"

• guanosine kinase activity database_cross_reference "EC:2.7.1.73"

  • source "skos:broadMatch"

hexosyltransferase activity http://purl.obolibrary.org/obo/GO_0016758

Removed

• hexosyltransferase activity definition "Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)."
  • database_cross_reference "GOC:jl"

Added

• hexosyltransferase activity definition "Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)."
  • database_cross_reference "EC:2.4.1.-"

hypoxanthine phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0004422

Removed

• hypoxanthine phosphoribosyltransferase activity definition "Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "GOC:curators"

  • database_cross_reference "EC:2.4.2.8"

• hypoxanthine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.8"

• hypoxanthine phosphoribosyltransferase activity database_cross_reference "RHEA:17973"

Added

• hypoxanthine phosphoribosyltransferase activity database_cross_reference "RHEA:17973"

  • source "skos:exactMatch"

• hypoxanthine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.8"

  • source "skos:broadMatch"

• hypoxanthine phosphoribosyltransferase activity definition "Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate."

  • database_cross_reference "RHEA:17973"

inosine kinase activity http://purl.obolibrary.org/obo/GO_0008906

Removed

• inosine kinase activity database_cross_reference "RHEA:21140"

• inosine kinase activity database_cross_reference "EC:2.7.1.73"

Added

• inosine kinase activity database_cross_reference "RHEA:21140"

  • source "skos:exactMatch"

• inosine kinase activity database_cross_reference "EC:2.7.1.73"

  • source "skos:broadMatch"

kaempferol 3-O-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0033834

Removed

• kaempferol 3-O-galactosyltransferase activity database_cross_reference "RHEA:15709"

• kaempferol 3-O-galactosyltransferase activity database_cross_reference "EC:2.4.1.234"

• kaempferol 3-O-galactosyltransferase activity definition "Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside."

  • database_cross_reference "EC:2.4.1.234"

• kaempferol 3-O-galactosyltransferase activity SubClassOf galactosyltransferase activity

Added

• kaempferol 3-O-galactosyltransferase activity database_cross_reference "EC:2.4.1.234"

  • source "skos:exactMatch"

• kaempferol 3-O-galactosyltransferase activity database_cross_reference "RHEA:15709"

  • source "skos:exactMatch"

• kaempferol 3-O-galactosyltransferase activity definition "Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside."

  • database_cross_reference "RHEA:15709"

• kaempferol 3-O-galactosyltransferase activity SubClassOf hexosyltransferase activity

linear malto-oligosaccharide phosphorylase activity http://purl.obolibrary.org/obo/GO_0102250

Removed

• linear malto-oligosaccharide phosphorylase activity database_cross_reference "EC:2.4.1.1"

• linear malto-oligosaccharide phosphorylase activity definition "Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.4.1.1"

• linear malto-oligosaccharide phosphorylase activity database_cross_reference "MetaCyc:RXN-12392"

• linear malto-oligosaccharide phosphorylase activity label "linear malto-oligosaccharide phosphorylase activity"

• linear malto-oligosaccharide phosphorylase activity SubClassOf hexosyltransferase activity

Added

• linear malto-oligosaccharide phosphorylase activity deprecated true

• linear malto-oligosaccharide phosphorylase activity label "obsolete linear malto-oligosaccharide phosphorylase activity"

• linear malto-oligosaccharide phosphorylase activity term replaced by "GO:0004645"

• linear malto-oligosaccharide phosphorylase activity comment "This term was obsoleted because it represents a specific substrate of 1,4-alpha-oligoglucan phosphorylase activity ; GO:0004645."

• linear malto-oligosaccharide phosphorylase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• linear malto-oligosaccharide phosphorylase activity definition "OBSOLETE. Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide."

  • database_cross_reference "GOC:pz"

maltodextrin phosphorylase activity http://purl.obolibrary.org/obo/GO_0031220

Added

• maltodextrin phosphorylase activity database_cross_reference "EC:2.4.1.1"
  • source "skos:broadMatch"

quercetin 3-O-beta:-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0102479

Removed

• quercetin 3-O-beta:-D-galactosyltransferase activity database_cross_reference "MetaCyc:RXN-14109"

• quercetin 3-O-beta:-D-galactosyltransferase activity definition "Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose = quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+."

  • database_cross_reference "EC:2.4.1.234"

  • database_cross_reference "GOC:pz"

• quercetin 3-O-beta:-D-galactosyltransferase activity label "quercetin 3-O-beta:-D-galactosyltransferase activity"

• quercetin 3-O-beta:-D-galactosyltransferase activity database_cross_reference "EC:2.4.1.234"

• quercetin 3-O-beta:-D-galactosyltransferase activity SubClassOf hexosyltransferase activity

Added

• quercetin 3-O-beta:-D-galactosyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• quercetin 3-O-beta:-D-galactosyltransferase activity definition "OBSOLETE. Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose = quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+."

  • database_cross_reference "GOC:pz"

• quercetin 3-O-beta:-D-galactosyltransferase activity label "obsolete quercetin 3-O-beta:-D-galactosyltransferase activity"

• quercetin 3-O-beta:-D-galactosyltransferase activity term replaced by "GO:0033834"

• quercetin 3-O-beta:-D-galactosyltransferase activity comment "This term was obsoleted because it represents a specific substrate of kaempferol 3-O-galactosyltransferase activity ; GO:0033834."

• quercetin 3-O-beta:-D-galactosyltransferase activity deprecated true

regulation of D-erythro-sphingosine kinase activity http://purl.obolibrary.org/obo/GO_1900022

Removed

• regulation of D-erythro-sphingosine kinase activity label "regulation of D-erythro-sphingosine kinase activity"

• regulation of D-erythro-sphingosine kinase activity in_subset gocheck_obsoletion_candidate

• regulation of D-erythro-sphingosine kinase activity definition "Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity."

  • database_cross_reference "GOC:signaling"

  • database_cross_reference "GOC:TermGenie"

• regulation of D-erythro-sphingosine kinase activity EquivalentTo biological regulation and (regulates some D-erythro-sphingosine kinase activity)

• regulation of D-erythro-sphingosine kinase activity SubClassOf regulation of lipid kinase activity

• regulation of D-erythro-sphingosine kinase activity SubClassOf regulates some D-erythro-sphingosine kinase activity

Added

• regulation of D-erythro-sphingosine kinase activity term tracker item "https://github.com/geneontology/go-ontology/issues/22455"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• regulation of D-erythro-sphingosine kinase activity deprecated true

• regulation of D-erythro-sphingosine kinase activity definition "OBSOLETE. Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity."

  • database_cross_reference "GOC:signaling"

  • database_cross_reference "GOC:TermGenie"

• regulation of D-erythro-sphingosine kinase activity label "obsolete regulation of D-erythro-sphingosine kinase activity"

• regulation of D-erythro-sphingosine kinase activity consider "GO:0019207"

• regulation of D-erythro-sphingosine kinase activity comment "This term was obsoleted because it represents a molecular function."

scutellarein 7-O-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0102467

Removed

• scutellarein 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28318"

• scutellarein 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein = UDP( + scutellarin + H+."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.4.1.253"

• scutellarein 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

Added

• scutellarein 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

  • source "skos:broadMatch"

• scutellarein 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28318"

  • source "skos:exactMatch"

• scutellarein 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: scutellarein + UDP-alpha-D-glucuronate = scutellarin + UDP."

  • database_cross_reference "RHEA:28318"

• scutellarein 7-O-glucuronosyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

sphinganine kinase activity http://purl.obolibrary.org/obo/GO_0008481

Removed

• sphinganine kinase activity database_cross_reference "RHEA:15465"

• sphinganine kinase activity has_related_synonym "sphingosine kinase activity"

• sphinganine kinase activity definition "Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate."

  • database_cross_reference "EC:2.7.1.91"

• sphinganine kinase activity database_cross_reference "EC:2.7.1.91"

• sphinganine kinase activity label "sphinganine kinase activity"

Added

• sphinganine kinase activity database_cross_reference "EC:2.7.1.91"

  • source "skos:exactMatch"

• sphinganine kinase activity database_cross_reference "RHEA:51496"

  • source "skos:exactMatch"

• sphinganine kinase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• sphinganine kinase activity has_related_synonym "sphinganine kinase activity"

• sphinganine kinase activity definition "Catalysis of the reaction: a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H+."

  • database_cross_reference "RHEA:51496"

• sphinganine kinase activity label "sphingosine kinase activity"

sucrose phosphorylase activity http://purl.obolibrary.org/obo/GO_0009018

Removed

• sucrose phosphorylase activity definition "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate."

  • database_cross_reference "EC:2.4.1.7"

• sucrose phosphorylase activity database_cross_reference "RHEA:24048"

Added

• sucrose phosphorylase activity definition "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate."

  • database_cross_reference "RHEA:24048"

• sucrose phosphorylase activity database_cross_reference "RHEA:24048"

  • source "skos:exactMatch"

wogonin 7-O-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0102468

Removed

• wogonin 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin = UDP + wogonin 7-O-beta-D-glucuronate + H+."

  • database_cross_reference "GOC:pz"

  • database_cross_reference "EC:2.4.1.253"

• wogonin 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

• wogonin 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28322"

Added

• wogonin 7-O-glucuronosyltransferase activity term tracker item "https://github.com/geneontology/go-ontology/issues/28070"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI)

• wogonin 7-O-glucuronosyltransferase activity database_cross_reference "RHEA:28322"

  • source "skos:exactMatch"

• wogonin 7-O-glucuronosyltransferase activity definition "Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin = UDP + wogonin 7-O-beta-D-glucuronate + H+."

  • database_cross_reference "RHEA:28322"

• wogonin 7-O-glucuronosyltransferase activity database_cross_reference "EC:2.4.1.253"

  • source "skos:broadMatch"

xanthine phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0000310

Removed

• xanthine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.22"

• xanthine phosphoribosyltransferase activity database_cross_reference "RHEA:10800"

• xanthine phosphoribosyltransferase activity definition "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate."

  • database_cross_reference "GOC:clt"

  • database_cross_reference "EC:2.4.2.22"

Added

• xanthine phosphoribosyltransferase activity definition "Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine."

  • database_cross_reference "RHEA:10800"

• xanthine phosphoribosyltransferase activity database_cross_reference "EC:2.4.2.22"

  • source "skos:exactMatch"

• xanthine phosphoribosyltransferase activity database_cross_reference "RHEA:10800"

  • source "skos:exactMatch"