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I had problems with a new MS feature.
see http://en.wikipedia.org/wiki/TCP_tuning and
https://technet.microsoft.com/en-us/magazine/2007.01.cableguy.aspx
We have a proprietary TCP tunnel with a really long RTT > 3 sec and a MSS of 21 kBytes to an embedded ftp client.
With throttling I tried to not send more than 21 kBytes per 3 seconds -> i.e. 7 kBytes/sec but this was not enough.
Note, this new microsoft feature can't not really disabled for one interface only!
To prevent a lot of TCP retransmissions and delayed ACK's I should be able to set the socket receive buffer and transmit buffer size.
I have prepared a patch to enable this feature using socket.setsockopt().