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📑Reports and bioinformatics analyses from internship in Indonesia

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Research topic

Pediatric Nutritional Medicine and Intestinal Microbiology (repository name is the acronym)

Figure 1. Clinical trial design.

🗺️ Field Work

During the internship, I did a research expedition to the East Nusa Tenggara Province (Kupang City & North Kodi Township). This experience involved participation in the organization and execution of a clinical trial, a significant endeavor aimed at advancing our understanding of probiotic efficacy.

The crux of my responsibilities revolved around assistanship of organization and coordination of a clinical trial. This trial focused on over 200 children distributed across 4 distinct groups. I have visited group №2 & group №4.

Blood and stool samples were systematically gathered from the participants.

Figure 2. Field work map. Dark blue dot - Jakarta, capital of Indonesia. Dark red dots - North Kodi Township & Kupang City.

Map made with rnaturalearth in RStudio

💻 Bioinformatic Works

🧬 Genomic Insights: Unraveling Safety Aspects of Probiotic Lpb. plantarum IS-10506

This internship report unveils a comprehensive genome-based safety assessment of the probiotic strain Lpb. plantarum IS-10506. The study explores bacteriocin clusters and CRISPR sequences, shedding light on its antimicrobial potential and defense mechanisms.

🧫 Microbial Insights: Examining Gut Differences in Growing Children

This internship report presents a multivariate analysis of the relationship between clinical metadata and microbiome characteristics in a comparative study of gut microbiota profiles in stunted and normal growing children aged 36-45 months. V3-V4 16s rRNA amplicon sequencing data from faecal samples of the children participating in the study were used for the analyses.

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