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Flye 2.8

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@mikolmogorov mikolmogorov released this 05 Aug 01:27
· 221 commits to flye since this release
  • Improvements in contiguity and speed for PacBio HiFi mode
  • Using the --meta k-mer selection strategy in isolate assemblies as well.
    This strategy is more robust to drops in coverage/contamination and requires less memory
  • 1.5-2x RAM footprint reduction for large assemblies (e.g. human ONT assembly now uses 400-500 Gb)
  • Genome size parameter is no longer required (it is still needed for downsampling through --asm-coverage)
  • Flye now can occasionally use overlaps shorter than "minOverlap" parameter to close disjointig gaps
  • Various improvements and bugfixes