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working with gene panels or single genes (e.g., NF1) in the nf-core/rnaseq pipeline #1472

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huma1995 opened this issue Dec 18, 2024 · 0 comments

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@huma1995
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huma1995 commented Dec 18, 2024

Are there any recommendations for working with gene panels or single genes (e.g., NF1) in the nf-core/rnaseq pipeline, especially regarding the use of specific FASTA and GTF files? I’ve encountered compatibility issues where tools like RSEM work fine, but STAR does not, when using gene-specific files. Would it be better not to provide specific parameters for genes and instead filter the results at the end? If so, how would that be achieved?

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