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@yafeiwang89 yafeiwang89 released this 17 Aug 19:29
· 11 commits to master since this release
0.2.0
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Learn about vigilant mode.

This release matches with version used in the paper Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture

In this release:

  • Use intracellular drug concentration in calculating drug effect
  • Update receptor dynamics, replication dynamics, export rate parameters and EC_50 to match with experimental data
  • Add negative feedback for ACE2 binding, endocytosis process
  • Pick up 3000 cells randomly binded with virion, rather than internalization in the beginning
  • Use Dirichlet nodes for all voxels in the simulation
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