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What pre-processing are required for SusieR? We don't need to remove LD but it looks like we need to centre our data? #204

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garyzhubc opened this issue Nov 3, 2023 · 2 comments
Open

What pre-processing are required for SusieR? We don't need to remove LD but it looks like we need to centre our data? #204

garyzhubc opened this issue Nov 3, 2023 · 2 comments

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@garyzhubc
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What pre-processing are required for SusieR? We don't need to remove LD but it looks like we need to centre our data?
@garyzhubc
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Both genotype and phenotype need to be standardized, am I right?

@pcarbo
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pcarbo commented Nov 3, 2023

@garyzhubc If you are using the susie function, for example, there is no need; the susie function includes options to center (intercept = TRUE) and/or standardize.

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@pcarbo @garyzhubc