MethDemon (fluctuating methylation clock deme-based oncology model in 1D) is a framework for simulating fluctuating CpG loci in a cancer population expanding via gland fission, of which only a predetermined number of glands are tracked and sampled.
The program is written in C++; apart from standard libraries, it requires the Boost C++ library.
git clone -b methdemon1d https://github.com/vesmanojlovic/methdemon
cd methdemon1d
Then modify the Makefile to include the path to your copy of boost and run
make all
Create a directory where you would like your outputs stored and make a copy of the config.dat file modified with your required parameters. From the repo parent directory run
bin/methdemon <output_dir_path> <config_file_name>
To clear logfiles and binaries run
make clean