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Biomarkers of Major Depressive Disorder: An Analysis of Macro-Scale Cortical Gradients

This study relies on an extensive, freely available dataset. (Yan et al., 2019) To run the analyses on your computer:

  1. Send a data access request & sign the data use agreement.
  2. Change the directory to jupyter_book: cd .../Rest-MDD-Gradients/jupyter_book.
  3. Install the required packages like so: pip install -r requirements.txt or pip3 install -r requirements.txt
  4. Retrieve & place to Rest-MDD-Gradients/jupyter_book:
    • the folder with fMRI timeseries: REST-meta-MDD-Phase1-Sharing/Results/ROISignals_FunImgARCWF (no GSR);
    • the .xlsx file containing the phenotypic data of participants.
  5. Run the Jupyter Notebooks.

The whole project can be viewed in the Jupyter Book: download the repository and access the file index.html at Rest-MDD-Gradients/jupyter_book/_build/html/index.html

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Macro-scale cortical gradients as biomarkers of MDD.

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