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doc fix
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mvfki committed Mar 21, 2024
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2 changes: 2 additions & 0 deletions NEWS.md
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- Ability to do downstream analysis on H5 data
- Pseudo-bulk should be easy because we are just aggregating cells.
- Wilcoxon might be a bit harder because ranks are calculated per gene but the H5 sparse data is column majored. Might need to find a fast on-disk transposition method.
- Fix runUINMF aborting criteria
- UINMF is capable of running with k > number of shared genes. Don't have to abort on it.

## rliger 2.0.0

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4 changes: 1 addition & 3 deletions vignettes/articles/STARmap_dropviz_vig.Rmd
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Expand Up @@ -66,10 +66,8 @@ Unshared Integrative Non-negative Matrix Factorization (UINMF) can be applied wi

In this tutorial, we set dataset specific lambda (regularization parameter) values to penalize the dataset specific effect differently.

Another noteworthy advantage of UINMF is that we are able to use a larger number of factors than there are shared features. We captilize on this by changing the default value of `k` to 40.

```{r factorization}
lig <- runUINMF(lig, k = 40, lambda = c(10, 1))
lig <- runUINMF(lig, k = 25, lambda = c(10, 1))
```

## Step 4: Quantile Normalization and Joint Clustering
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