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Extracting target from genes using annotation file #1

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nimarafati opened this issue Sep 4, 2024 · 0 comments
Open
3 tasks

Extracting target from genes using annotation file #1

nimarafati opened this issue Sep 4, 2024 · 0 comments
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enhancement New feature or request

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@nimarafati
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At the moment, ClustalW is used to do MSA and identify shared regions among all the isoforms. As an alternative we can use a coordinate-based approach to identify overlapping regions among the exons within each gene. To do so we can use the following steps:

  • Extracting annotation information of given gene provided by the user from gtf file
  • Calculating overlap of the exons
  • Choose the regions with highest overlap representing presence of the segment in all the isofrom
@nimarafati nimarafati added the enhancement New feature or request label Sep 4, 2024
@nimarafati nimarafati self-assigned this Sep 4, 2024
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