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At the moment, ClustalW is used to do MSA and identify shared regions among all the isoforms. As an alternative we can use a coordinate-based approach to identify overlapping regions among the exons within each gene. To do so we can use the following steps:
Extracting annotation information of given gene provided by the user from gtf file
Calculating overlap of the exons
Choose the regions with highest overlap representing presence of the segment in all the isofrom
The text was updated successfully, but these errors were encountered:
At the moment, ClustalW is used to do MSA and identify shared regions among all the isoforms. As an alternative we can use a coordinate-based approach to identify overlapping regions among the exons within each gene. To do so we can use the following steps:
The text was updated successfully, but these errors were encountered: