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FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

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leeoesterreich/npjBreast_2019

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npjBreast_2019

Transcript counts from all samples were quantified with Salmon v.0.8.2 and converted to gene-level counts with tximport. The gene-level counts from all studies were then normalized together using TMM with edgeR. Log2 transformed TMM-normalized counts per million: log2 (TMM-CPM + 1) expression values were used for the analysis.

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FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

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